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Clinical Rheumatology

, Volume 21, Issue 4, pp 328–329 | Cite as

Vasculitis Induced by Zafirlukast Therapy

  • M. Soy
  • H. Ozer
  • A. Canataroglu
  • D. Gumurdulu
  • E. Erken
Case Report

Abstract

Zafirlukast is a leukotriene inhibitor that has recently been approved for the prophylaxis of asthma. Although this new product has been well accepted because of its convenient dosing and relatively few side effects, several cases of Churg–Strauss syndrome have been reported to be associated with its use. In this paper we describe the case of a 54-year-old white man with no history of corticosteroid therapy in whom leukocytoclastic vasculitis, hepatitis and eosinophilia developed while he was on zafirlukast therapy for mild asthma.

Key words:Churg–Strauss syndrome – Zafirlukast 

Copyright information

© Clinical Rheumatology 2002

Authors and Affiliations

  • M. Soy
    • 1
  • H. Ozer
    • 1
  • A. Canataroglu
    • 1
  • D. Gumurdulu
    • 1
  • E. Erken
    • 1
  1. 1.Cukurova University Faculty of Medicine, Adana, TurkeyTurkey

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