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Healthcare utilization and costs among patients with psoriasis and psoriatic arthritis in the USA–a retrospective study of claims data from 2009 to 2020

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Abstract

Objectives

To compare healthcare resource utilization and costs among patients with psoriasis, psoriatic arthritis (PsA), and a control group of patients without psoriasis and PsA in the USA.

Methods

The IBM® MarketScan® Commercial Database was used to identify three adult patient groups from 1/1/2009 through 4/30/2020: (1) Psoriasis: ≥ 2 diagnoses ≥ 30 days apart for psoriasis (no PsA diagnoses); (2) PsA: ≥ 2 diagnoses for PsA; (3) Control: no psoriasis or PsA diagnoses in their entire claims records. Patients with comorbid rheumatoid arthritis, ankylosing spondylitis, Crohn’s disease, or ulcerative colitis were excluded from the analyses. Controls were matched 1:1 to psoriasis and PsA patients based on age, gender, index year, and number of non-rheumatological comorbidities. Healthcare resource utilization and costs (in 2019 USD) were evaluated descriptively and through mixed models for five years of follow-up.

Results

A total of 142,531 psoriasis and 21,428 PsA patients were matched to the control group (N = 163,959). Annual all-cause healthcare costs per patient were $7,470, $11,062, and $29,742 for the control, psoriasis, and PsA groups, respectively. All-cause healthcare costs increased over time and were significantly greater among PsA vs. psoriasis (p < 0.0001) and the control groups (p < 0.0001). Across all categories of healthcare resources, utilization was greatest among patients with PsA and lowest in the control group.

Conclusion

Annual healthcare costs and resource utilization were significantly higher with PsA compared with psoriasis and the control group, confirming the substantial economic burden of PsA. The cost disparity between these patient groups highlights a continued unmet medical need.

Key Points

• Patients with PsA incurred significantly greater healthcare resource utilization and costs than patients with psoriasis and patients without psoriasis and PsA.

• Significantly greater costs and healthcare resource utilization were also observed among patients with psoriasis compared with patients without psoriasis and PsA.

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Funding

Funding for this research was provided by Janssen Pharmaceutica.

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Authors and Affiliations

  1. Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    J. F. Merola

  2. Amaris, Health Economics and Market Access, Paris, France

    N. Dennis & M. Pacou

  3. Janssen Scientific Affairs, LLC, Horsham, PA, USA

    S. D. Chakravarty

  4. Drexel University College of Medicine, Philadelphia, PA, USA

    S. D. Chakravarty

  5. Janssen Immunology Global Commercial Strategy Organization, Horsham, PA, USA

    R. Villacorta, I. Lin, M. Shawi, T. Baker & S. Peterson

  6. Amaris, Health Economics and Market Access, Jersey City, NJ, USA

    L. Mesana

  7. Janssen R&D, LLC, Titusville, NJ, USA

    Y. Wang

Authors
  1. J. F. Merola
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  4. R. Villacorta
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  5. L. Mesana
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  6. I. Lin
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  11. S. Peterson
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Corresponding author

Correspondence to J. F. Merola.

Ethics declarations

Ethics approval

The use of the IBM MarketScan® databases was reviewed by the New England Institution Review Board and was determined to be exempt from broad IRB approval, as this research project did not involve human subject research.

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Conflict of interest

JFM is a consultant and/or investigator for Abbvie, Amgen, Bayer, Dermavant, Eli Lilly, Novartis, Janssen, UCB, Celgene, Sanofi-Regeneron, Biogen, Pfizer, BMS, and LEO Pharma. IL, TB, YW, and RV are employees of Janssen Pharmaceutical companies that manufacture products indicated for psoriasis and PsA. SDC, SP, and MS are employees of Janssen Scientific Affairs, LLC and shareholders of Johnson & Johnson, of which Janssen Scientific Affairs, LLC is a wholly owned subsidiary. ND, LM, and MP have no conflicts to disclose.

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Merola, J.F., Dennis, N., Chakravarty, S.D. et al. Healthcare utilization and costs among patients with psoriasis and psoriatic arthritis in the USA–a retrospective study of claims data from 2009 to 2020. Clin Rheumatol 40, 4061–4070 (2021). https://doi.org/10.1007/s10067-021-05713-8

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  • DOI: https://doi.org/10.1007/s10067-021-05713-8

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