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Comment on “Impact of TNF-Α inhibitor on lipid profile and atherogenic index of plasma in axial spondyloarthritis: 2-year follow-up data from the catholic axial spondyloarthritis cohort (CASCO)”

  • Erkan CureEmail author
  • Medine Cumhur Cure
Letter to the Editor
  • 9 Downloads

Dear Sir,

We read with great pleasure the very important study evaluating the impact of tumor necrosis factor-alpha inhibitor (TI) on lipid profile and atherogenic index of plasma (AIP) in axial spondyloarthritis by Min HK et al. [1]. We would like to draw attention to some important points in this valuable study. In their study [1], the standard deviations of the AIP and cholesterol change difference values are too large. Both groups do not show the homogeneous distribution, for these values ​​must be given as median (range). The authors should use the Mann-Whitney U test instead of the t-test to compare nonhomogeneous data. P values may change with the proper statistical evaluation.

Ankylosing spondylitis (AS) is a rheumatologic disease with frequent cardiac involvement [2]. When the two groups’ baseline values were examined, the disease duration was significantly higher in the TI group than without the TI (TW) group [1]. The longer the disease duration will increase cardiovascular...

Notes

Compliance with ethical standards

Conflict of interest

None.

References

  1. 1.
    Min HK, Lee J, Ju JH, Park SH, Kwok SK (2019) Impact of TNF-α inhibitor on lipid profile and atherogenic index of plasma in axial spondyloarthritis: 2-year follow-up data from the Catholic axial Spondyloarthritis COhort (CASCO). Clin Rheumatol 1–7.  https://doi.org/10.1007/s10067-019-04767-z
  2. 2.
    Cure E, Icli A, Uslu AU, Sakiz D, Cure MC, Baykara RA (2018) Atherogenic index of plasma: a useful marker for subclinical atherosclerosis in ankylosing spondylitis: AIP associate with cIMT in AS. Clin Rheumatol 37:1273–1280CrossRefGoogle Scholar
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Copyright information

© International League of Associations for Rheumatology (ILAR) 2020

Authors and Affiliations

  1. 1.Department of Internal MedicineOta & Jinemed HospitalIstanbulTurkey
  2. 2.Department of BiochemistryPrivate PracticeIstanbulTurkey

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