Comment on “Impact of TNF-Α inhibitor on lipid profile and atherogenic index of plasma in axial spondyloarthritis: 2-year follow-up data from the catholic axial spondyloarthritis cohort (CASCO)”
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We read with great pleasure the very important study evaluating the impact of tumor necrosis factor-alpha inhibitor (TI) on lipid profile and atherogenic index of plasma (AIP) in axial spondyloarthritis by Min HK et al. . We would like to draw attention to some important points in this valuable study. In their study , the standard deviations of the AIP and cholesterol change difference values are too large. Both groups do not show the homogeneous distribution, for these values must be given as median (range). The authors should use the Mann-Whitney U test instead of the t-test to compare nonhomogeneous data. P values may change with the proper statistical evaluation.
Ankylosing spondylitis (AS) is a rheumatologic disease with frequent cardiac involvement . When the two groups’ baseline values were examined, the disease duration was significantly higher in the TI group than without the TI (TW) group . The longer the disease duration will increase cardiovascular...
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Conflict of interest
- 1.Min HK, Lee J, Ju JH, Park SH, Kwok SK (2019) Impact of TNF-α inhibitor on lipid profile and atherogenic index of plasma in axial spondyloarthritis: 2-year follow-up data from the Catholic axial Spondyloarthritis COhort (CASCO). Clin Rheumatol 1–7. https://doi.org/10.1007/s10067-019-04767-z