Association of radiographic findings in hand X-ray with clinical features and autoantibodies in patients with systemic sclerosis
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• Hand X-ray abnormalities were observed in approximately two-thirds of patients with SSc.
• Erosive osteoarthritis was more prevalent in SSc patients than general population.
• Hand X-ray findings were associated with disease duration, organ involvements, and SSc-associated autoantibodies, reflecting underlying pathogenesis.
KeywordsAutoantibodies Hand Radiography Systemic sclerosis
Compliance with ethical standards
This study was approved by the ethics committee of Keio University School of Medicine (approval number: 20130506). The requirement for informed consent from the patients was waived according to the regulation in Japan.
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