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Clinical Rheumatology

, Volume 38, Issue 2, pp 583–584 | Cite as

Osteoarthritis: a call for research on central pain mechanism and personalized prevention strategies

  • Jorge Hugo VillafañeEmail author
  • Kristin Valdes
  • Paolo Pedersini
  • Pedro Berjano
Brief Report

Abstract

Osteoarthritis (OA) is one of the world’s leading causes of pain, disability. Symptomatic OA should be suspected in patients with pain in the joints of the fingers, shoulders, hips, knees, or ankles, especially if those patients are older than 40 years. The socioeconomic cost of treating the condition and the burden of the expense is growing with the increasing and aging population. Joint-preserving interventions currently used to manage the condition include joint-protection technique instruction, manual therapy, adaptive equipment provision and instruction, heat modalities, orthoses, strengthening and range-of-motion exercises, adaptive technique instruction, patient education in symptom control techniques, and provision of a home exercise program. Some show potential, but at present, few have a proven ability to arrest or delay disease progression. Recent research regarding central pain mechanisms indicates treating central pain sensitization may be an effective treatment approach. Additional research is required to determine the efficacy of treatment and symptom management of OA.

Keywords

Life style Osteoarthritis Pain 

Notes

Author contributions

J.H.V: concept development, design, literature search, and writing. KV: literature search and writing. P. P: literature search and writing. P. B: literature search and writing.

Compliance with ethical standards

Disclosure

None.

References

  1. 1.
    Clauw DJ, Hassett AL (2017) The role of centralised pain in osteoarthritis. Clin Exp Rheumatol, 35 Suppl 107(5):79–84Google Scholar
  2. 2.
    Focht BC (2012) Move to improve: how knee osteoarthritis patients can use exercise to enhance quality of life. ACSMs Health Fit J 16(5):24–28.  https://doi.org/10.1249/FIT0b013e318264cae8 CrossRefGoogle Scholar
  3. 3.
    Fransen M, Simic M, Harmer AR (2014) Determinants of MSK health and disability: lifestyle determinants of symptomatic osteoarthritis. Best Pract Res Clin Rheumatol 28(3):435–460.  https://doi.org/10.1016/j.berh.2014.07.002 CrossRefGoogle Scholar
  4. 4.
    Kosek, E., & Ordeberg, G. (2000). Lack of pressure pain modulation by heterotopic noxious conditioning stimulation in patients with painful osteoarthritis before, but not following, surgical pain relief Pain, 88(1), 69–78Google Scholar
  5. 5.
    Lue S, Koppikar S, Shaikh K, Mahendira D, Towheed TE (2017) Systematic review of non-surgical therapies for osteoarthritis of the hand: an update. Osteoarthr Cartil 25(9):1379–1389.  https://doi.org/10.1016/j.joca.2017.05.016 CrossRefGoogle Scholar
  6. 6.
    Mobasheri A, Batt M (2016) An update on the pathophysiology of osteoarthritis. Ann Phys Rehabil Med 59(5–6):333–339.  https://doi.org/10.1016/j.rehab.2016.07.004 CrossRefGoogle Scholar
  7. 7.
    Szychlinska MA, Castrogiovanni P, Trovato FM, Nsir H, Zarrouk M, Lo Furno D, Musumeci G (2018) Physical activity and Mediterranean diet based on olive tree phenolic compounds from two different geographical areas have protective effects on early osteoarthritis, muscle atrophy and hepatic steatosis. Eur J Nutr.  https://doi.org/10.1007/s00394-018-1632-2
  8. 8.
    Villafane JH (2018) Does “time heal all wounds” still have a future in osteoarthritis? Clin Exp Rheumatol 36(3):513Google Scholar
  9. 9.
    Villafane JH, Bishop MD, Fernandez-de-Las-Penas C, Langford D (2013) Radial nerve mobilisation had bilateral sensory effects in people with thumb carpometacarpal osteoarthritis: a randomised trial. J Physiother 59(1):25–30.  https://doi.org/10.1016/S1836-9553(13)70143-7 CrossRefGoogle Scholar

Copyright information

© International League of Associations for Rheumatology (ILAR) 2018

Authors and Affiliations

  • Jorge Hugo Villafañe
    • 1
    Email author
  • Kristin Valdes
    • 2
  • Paolo Pedersini
    • 1
  • Pedro Berjano
    • 3
  1. 1.IRCCS Fondazione Don Carlo GnocchiMilanItaly
  2. 2.Gannon UniversityRuskinUSA
  3. 3.IRCCS Istituto Ortopedico GaleazziMilanItaly

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