Osteoarthritis: a call for research on central pain mechanism and personalized prevention strategies
Osteoarthritis (OA) is one of the world’s leading causes of pain, disability. Symptomatic OA should be suspected in patients with pain in the joints of the fingers, shoulders, hips, knees, or ankles, especially if those patients are older than 40 years. The socioeconomic cost of treating the condition and the burden of the expense is growing with the increasing and aging population. Joint-preserving interventions currently used to manage the condition include joint-protection technique instruction, manual therapy, adaptive equipment provision and instruction, heat modalities, orthoses, strengthening and range-of-motion exercises, adaptive technique instruction, patient education in symptom control techniques, and provision of a home exercise program. Some show potential, but at present, few have a proven ability to arrest or delay disease progression. Recent research regarding central pain mechanisms indicates treating central pain sensitization may be an effective treatment approach. Additional research is required to determine the efficacy of treatment and symptom management of OA.
KeywordsLife style Osteoarthritis Pain
J.H.V: concept development, design, literature search, and writing. KV: literature search and writing. P. P: literature search and writing. P. B: literature search and writing.
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- 1.Clauw DJ, Hassett AL (2017) The role of centralised pain in osteoarthritis. Clin Exp Rheumatol, 35 Suppl 107(5):79–84Google Scholar
- 4.Kosek, E., & Ordeberg, G. (2000). Lack of pressure pain modulation by heterotopic noxious conditioning stimulation in patients with painful osteoarthritis before, but not following, surgical pain relief Pain, 88(1), 69–78Google Scholar
- 7.Szychlinska MA, Castrogiovanni P, Trovato FM, Nsir H, Zarrouk M, Lo Furno D, Musumeci G (2018) Physical activity and Mediterranean diet based on olive tree phenolic compounds from two different geographical areas have protective effects on early osteoarthritis, muscle atrophy and hepatic steatosis. Eur J Nutr. https://doi.org/10.1007/s00394-018-1632-2
- 8.Villafane JH (2018) Does “time heal all wounds” still have a future in osteoarthritis? Clin Exp Rheumatol 36(3):513Google Scholar