Systemic sclerosis-rheumatoid arthritis overlap syndrome complicated with Sweet’s syndrome
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Herein, we report a case of a 34-year-old woman with systemic sclerosis (SSc)-rheumatoid arthritis (RA) overlap syndrome (OS) complicated with Sweet’s syndrome. OS has been defined as entities satisfying classification criteria of at least two connective tissue diseases (CTD) occurring at the same or at different times in the same patient. The CTD include RA, SSc, systemic lupus erythematosus (SLE), polymyositis, and dermatomyositis. Sweet’s syndrome also known as acute febrile neutrophilic dermatosis was first described by Robert Sweet in 1964. Sweet’s syndrome is characterized by fever, neutrophilia, erythematous skin lesions, and a diffuse dermal infiltrate of mature neutrophils. There are sets of associations that we will discuss in this article between OS and Sweet’s syndrome.
KeywordsOverlap syndrome Rheumatoid arthritis Sweet’s syndrome Systemic sclerosis
Abbreviation and acronym
American College of Rheumatology
connective tissue diseases
systemic lupus erythematosus
This study was supported by the National Natural Science Foundation of China (81371731). Milstein Medical Asian American Partnership Foundation (2017, Dermatology), and Education Reform Projects of Peking Union Medical College (No. 2016zlgc0106).
Compliance with ethical standards
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