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Clinical Rheumatology

, Volume 34, Issue 6, pp 1145–1148 | Cite as

Bilateral dexamethasone intravitreal implant in a young patient with Vogt-Koyanagi-Harada disease and refractory uveitis

  • Maria Eugenia Latronico
  • Donato Rigante
  • Francesco Caso
  • Luca CantariniEmail author
  • Luisa Costa
  • Laura Nieves-Martín
  • Claudio Traversi
  • Rossella Franceschini
Case Based Review

Abstract

Vogt-Koyanagi-Harada disease (VKHD) is a multisystemic disorder characterized by granulomatous panuveitis with exudative retinal detachments, often associated with neurologic and cutaneous manifestations. Therapy relies mainly on the use of corticosteroids, administrated as oral or intravenous high-dose pulses, and immunosuppressants. However, since macular edema and retinal detachment can often be refractory to systemic therapies, intravitreal triamcinolone acetate has been used successfully. Herein, we report the first case of refractory bilateral panuveitis in a young patient with VKHD successfully treated with dexamethasone intravitreal implant.

Keywords

Prednisone Therapy Uveitis Vogt-Koyanagi-Harada disease (VKHD) 

Notes

Disclosures

None.

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Copyright information

© Clinical Rheumatology 2014

Authors and Affiliations

  • Maria Eugenia Latronico
    • 1
  • Donato Rigante
    • 2
  • Francesco Caso
    • 3
    • 4
  • Luca Cantarini
    • 3
    Email author
  • Luisa Costa
    • 5
  • Laura Nieves-Martín
    • 3
    • 6
  • Claudio Traversi
    • 1
  • Rossella Franceschini
    • 1
  1. 1.Ophthalmology and Neurosurgery DepartmentUniversity of SienaSienaItaly
  2. 2.Institute of PediatricsUniversità Cattolica Sacro CuoreRomeItaly
  3. 3.Research Center of Systemic Autoimmune and Autoinflammatory Diseases, Rheumatology Unit, Policlinico Le ScotteUniversity of SienaSienaItaly
  4. 4.Rheumatology Unit, Department of Medicine DIMEDUniversity of PaduaPaduaItaly
  5. 5.Rheumatology Unit, Department of Clinical Medicine and SurgeryUniversity Federico IINaplesItaly
  6. 6.Rheumatology Service, Hospital Regional Universitario Carlos HayaUniversity of MálagaMálagaSpain

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