Clinical Rheumatology

, Volume 31, Issue 6, pp 1019–1025 | Cite as

Life-threatening spontaneous splenic rupture with systemic lupus erythematosus: case report and literature review

  • Jie Han
  • Ning Li
  • JiaYi Wang
  • JieRu Zhou
  • Jie Zhang
Case Based Review


Although involvement of the reticuloendothelial system in systemic lupus erythematosus (SLE) is a well-recognised concomitant of the disease, spontaneous splenic rupture is an unusual occurrence. We observed a 54-year-old woman with SLE who had spontaneous splenic rupture during the late course of the disease and showed some changes histopathologically. The courses and the clinical characteristics of such patients are reviewed, and the diagnosis and treatment of these cases are discussed. Early evaluation for SLE patients with spontaneous splenic rupture should be considered and included in the differential diagnosis of acute abdomen, as it may affect follow-up and treatment, although the condition is rare.


Spleen Spontaneous rupture Systemic lupus erythematosus 



This work was partly funded by a Research Grant for Health Science and Technology development and innovation of Pudong New Area of Shanghai (Grant No. PKJ2011-Y06).

The authors thank Prof. SongGuo Zheng for his review of the manuscript and his insightful comments.




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Copyright information

© Clinical Rheumatology 2012

Authors and Affiliations

  • Jie Han
    • 1
  • Ning Li
    • 1
  • JiaYi Wang
    • 1
  • JieRu Zhou
    • 1
  • Jie Zhang
    • 1
  1. 1.Department of RheumatologyTong Ji University Affiliated Shanghai East HospitalShanghaiChina

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