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Clinical Rheumatology

, Volume 30, Issue 8, pp 1075–1080 | Cite as

Recently diagnosed axial spondyloarthritis: gender differences and factors related to delay in diagnosis

  • Gleb Slobodin
  • Iris Reyhan
  • Nina Avshovich
  • Alexandra Balbir-Gurman
  • Nina Boulman
  • Mona Elias
  • Joy Feld
  • Reuven Mader
  • Doron Markovitz
  • Doron Rimar
  • Itzhak Rosner
  • Michael Rozenbaum
  • Devy Zisman
  • Majed Odeh
Original Article

Abstract

A cohort of patients with recently diagnosed axial spondyloarthritis (SpA) was characterized with emphasis on gender differences and factors leading to delay in diagnosis. Clinical, laboratory, and imaging data of 151 consecutive patients diagnosed with ankylosing spondylitis or undifferentiated SpA in 2004–2009 and satisfying the new ASAS classification criteria for axial SpA, was collected and analyzed. Seventy-nine men and 72 women were enrolled. Both groups (men and women) had similar age of onset of disease-related symptoms, as well as similar delay time to diagnosis, follow-up duration and frequency of anti-TNF treatment. Inflammatory back pain, as a first symptom related to SpA, was reported more often by men, while women had more pelvic, heel, and widespread pain (WP) during the course of the disease. At the time of diagnosis, men were more limited in chest expansion and showed increased occiput-to-wall distance compared to women. Elevated erythrocyte sedimentation rate and/or C-reactive protein were detected in a similar proportion of men and women. Presence of WP in women almost doubled the delay in the diagnosis of SpA. No other differences in disease presentation or burden were demonstrated to correlate with delay in diagnosis.

Keywords

Ankylosing spondylitis Axial spondyloarthritis Gender differences 

Notes

Disclosures

None

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Copyright information

© Clinical Rheumatology 2011

Authors and Affiliations

  • Gleb Slobodin
    • 1
    • 7
  • Iris Reyhan
    • 7
  • Nina Avshovich
    • 2
  • Alexandra Balbir-Gurman
    • 3
    • 7
  • Nina Boulman
    • 4
    • 7
  • Mona Elias
    • 4
    • 5
  • Joy Feld
    • 5
  • Reuven Mader
    • 6
    • 7
  • Doron Markovitz
    • 3
    • 7
  • Doron Rimar
    • 4
  • Itzhak Rosner
    • 4
    • 7
  • Michael Rozenbaum
    • 4
    • 7
  • Devy Zisman
    • 5
  • Majed Odeh
    • 1
    • 7
  1. 1.Internal Medicine ABnai Zion Medical CenterHaifaIsrael
  2. 2.Internal Medicine CHillel Yaffe Medical CenterHaderaIsrael
  3. 3.B. Shine Rheumatology UnitRambam Medical CenterHaifaIsrael
  4. 4.Division of RheumatologyBnai-Zion Medical CenterHaifaIsrael
  5. 5.Department of RheumatologyCarmel and Lin Medical CentersHaifaIsrael
  6. 6.Department of RheumatologyHaemek Medical CenterAfulaIsrael
  7. 7.Ruth & Bruce Rappaport Faculty of MedicineTechnionHaifaIsrael

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