Clinical Rheumatology

, 28:301

Anti-Ro antibody and cutaneous vasculitis in systemic lupus erythematosus

  • Márcio Veronesi Fukuda
  • Simone Chinwa Lo
  • Cláudia Salvini de Almeida
  • Samuel Katsuyuki Shinjo
Original Article

Abstract

Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease with various clinical and serological manifestations. Previous studies have shown the association of SLE and anti-Ro antibody with a series of clinical manifestations. We investigated this association in Brazilian patients with SLE. Five hundred and nine consecutive patients who fulfilled the revised American College of Rheumatology criteria for the SLE were enrolled in the study from June to December 2007. All patients were from our Service of Rheumatology, School of Medicine, University of São Paulo, Brazil. Frequencies of a series of laboratorial and clinical manifestations were calculated. Anti-Ro antibody was associated to anti-La antibody, female, and cutaneous vasculitis. In multivariate analysis, patients with anti-Ro antibody has 1.63 (95% CI 1.07–2.50) more risk to develop cutaneous vasculitis than patients without this antibody. Our data have demonstrated that anti-Ro antibody is an independent useful serologic marker for cutaneous vasculitis.

Keywords

Antibody anti-La Antibody anti-Ro Cutaneous manifestation Systemic lupus erythematosus Vasculitis 

Copyright information

© Clinical Rheumatology 2008

Authors and Affiliations

  • Márcio Veronesi Fukuda
    • 1
  • Simone Chinwa Lo
    • 1
  • Cláudia Salvini de Almeida
    • 1
  • Samuel Katsuyuki Shinjo
    • 1
  1. 1.Division of Rheumatology, School of MedicineUniversity of São PauloSão PauloBrazil

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