Advertisement

Clinical Rheumatology

, 27:1283 | Cite as

The relationship between benign joint hypermobility syndrome and carpal tunnel syndrome

  • I. Aktas
  • D. Ofluoglu
  • T. Albay
Original Article

Abstract

Benign joint hypermobility syndrome (BJHS) is defined as the presence of musculoskeletal symptoms in persons with generalized joint laxity in the absence of systemic rheumatologic disease. There is an association between soft tissue rheumatism, entrapment neuropathies, and BJHS. The purpose of the study was to identify the relationship between BJHS and carpal tunnel syndrome (CTS). Ninety patients were included in the prospective controlled study. All selected participants were referred to our electrophysiological laboratory with clinical diagnosis of CTS. Subsequently, subjects were divided into two groups as group I and II. Group I included patients with CTS and group II had patients without CTS based on electrophysiological findings. All subjects were assessed for existing BJHS by using the Brighton 1998 criteria. Fifty-five patients were recruited into group I (CTS) and 35 subjects were in group II. The mean age in group I and II was 49.5 ± 10.8 and 40 ± 9.9 years, respectively. The subjects in group II were younger than those in group I (p < 0.05). The mean Beighton score was 2.04 ± 2.7 and 1 ± 1.68 in groups I and II, respectively. In patients with CTS, BJHS rate was markedly higher than those in patients without CTS with respect to Brighton 1998 criteria (p < 0.0001). There was a positive correlation between CTS and BJHS (r = 0.59, p = 0.0001). Consequently, we suggested that BJHS could be a predisposing factor for CTS or vice versa.

Keywords

Beighton score Benign joint hypermobility syndrome Brighton criteria Carpal tunnel syndrome Entrapment neuropathy Hypermobility 

References

  1. 1.
    Simmonds JV, Keer RJ (2007) Hypermobility and the hypermobility syndrome. Man Ther 12:298–309PubMedCrossRefGoogle Scholar
  2. 2.
    Beighton P, Solomon L, Soskolne CL (1973) Articular mobility in an African population. Ann Rheum Dis 32:413–418PubMedCrossRefGoogle Scholar
  3. 3.
    Larsson LG, Baum J, Mudholkar GS (1987) Hypermobility: features and differential incidence between the sexes. Arthritis Rheum 30:1426–1430PubMedCrossRefGoogle Scholar
  4. 4.
    Rikken-Bultman DG, Wellink L, van Dongen PW (1997) Hypermobility in two Dutch school populations. Eur J Obstet Gynecol Reprod Biol 73:189–192PubMedCrossRefGoogle Scholar
  5. 5.
    Hakim A, Grahame R (2003) Joint hypermobility. Best Pract Res Clin Rheumatol 17:989–1004PubMedCrossRefGoogle Scholar
  6. 6.
    Seckin U, Sonel-Tur B, Yılmaz O, Yagcı I, Bodur H, Arasil T (2004) The prevalence of joint hypermobility among high school students. Rheumatol Int 25:260–263PubMedCrossRefGoogle Scholar
  7. 7.
    Nordstrom DL, Vierkant RA, DeStefano F, Layde PM (1997) Risk factors for carpal tunnel syndrome in a general population. Occup Environ Med 54:734–740PubMedCrossRefGoogle Scholar
  8. 8.
    de Krom MC, Kester AD, Knipschild PG, Spaans F (1990) Risk factors for carpal tunnel syndrome. Am J Epidemiol 132:1102–1110PubMedGoogle Scholar
  9. 9.
    Grahame R, Bird HA, Child A (2000) The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobility syndrome (BJHS). J Rheumatol 27(7):1777–1779PubMedGoogle Scholar
  10. 10.
    March LM, Francis H, Webb J (1988) Benign joint hypermobility with neuropathies: documentation and mechanism of median, sciatic, and common peroneal nerve compression. Clin Rheumatol 7:35–40PubMedCrossRefGoogle Scholar
  11. 11.
    Grahame R (1998) Regional and heritable bone and collagen diseases. In: Klippel JH, Dieppe PA (eds) Rheumatology. 2nd edn. Mosby, Philadelphia, pp 8.51.1–8.51.6Google Scholar
  12. 12.
    Stevens JC (1997) AAEM minimonograph #26: the electrodiagnosis of carpal tunnel syndrome. American Association of Electrodiagnostic Medicine. Muscle Nerve 20:1477–1786PubMedCrossRefGoogle Scholar
  13. 13.
    Szabo RM (1998) Carpal tunnel syndrome as a repetitive motion disorder. Clin Orthop 351:78–89PubMedGoogle Scholar
  14. 14.
    Solomon DH, Katz JN, Bohn R, Mogun H, Avorn J (1999) Nonoccupational risk factors for carpal tunnel syndrome. J Gen Intern Med 14:310–314PubMedCrossRefGoogle Scholar
  15. 15.
    Bozek M, Gaździk TS (2001) The value of clinical examination in the diagnosis of carpal tunnel syndrome. Ortop Traumatol Rehabil 30(3):357–360Google Scholar
  16. 16.
    Hall MG, Ferrell WR, Sturrock RD, Hamblen DL, Baxendale RH (1995) The effect of the hypermobility syndrome on knee joint proprioception. Br J Rheumatol 34:121–125PubMedCrossRefGoogle Scholar
  17. 17.
    Ferrell WR, Tennant N, Sturrock RD, Ashton L, Creed G, Brydson G, Rafferty D (2004) Amelioration of symptoms by enhancement of proprioception in patients with joint hypermobility syndrome. Arthritis Rheum 50:3323–3328PubMedCrossRefGoogle Scholar
  18. 18.
    Harinstein D, Buckingham EB, Braun T, Oral K, Baumon DH, Killian PJ, Bidula LP (1988) Systemic joint laxity is associated with temporomandibular joint dysfunction. Arthritis Rheum 31:1259–1264PubMedCrossRefGoogle Scholar
  19. 19.
    Rawi ZA, Nessan AH (1997) Joint hypermobility in patients with chondromalacia patella. Br J Rheumatol 36:1324–1327CrossRefGoogle Scholar
  20. 20.
    Ofluoglu D, Gunduz OH, Kul-Panza E, Guven Z (2006) Hypermobility in women with fibromyalgia syndrome. Clin Rheumatol 25:291–293PubMedCrossRefGoogle Scholar
  21. 21.
    Grahame R (1971) Joint hypermobility: clinical aspects. Proc R Soc Med 64:32–34Google Scholar
  22. 22.
    Hassan A, El-Shahaly HA, El-Sherif AK (1991) Is the benign joint hypermobility syndrome benign? Clin Rheumatol 10:302–327CrossRefGoogle Scholar
  23. 23.
    Beighton P, Grahame R, Bird H (eds) (1983) In: Hypermobility of joints. Springer, New York, p 178Google Scholar

Copyright information

© Clinical Rheumatology 2008

Authors and Affiliations

  1. 1.Physical Medicine and Rehabilitation DepartmentSaygi HospitalIstanbulTurkey
  2. 2.Physical Medicine and Rehabilitation DepartmentUniversal Hospitals GroupIstanbulTurkey
  3. 3.Neurology DepartmentSaygi HospitalIstanbulTurkey
  4. 4.Ozel Saygi Hastanesi Fizik Tedavi ve Rehabilitasyon BolumuSultanbeyli/IstanbulTurkey

Personalised recommendations