Clinical Rheumatology

, 27:1073 | Cite as

Fatal Kikuchi–Fujimoto disease associated with SLE and hemophagocytic syndrome: a case report

Case Report

Abstract

Kikuchi–Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare, benign, autoimmune condition characterized by lymphadenopathy, fever, and neutropenia. KFD can frequently mimic various diseases including infection, malignancy, and autoimmune disease. KFD has also been infrequently reported in association with SLE, which can be diagnosed previously, simultaneously, or after the diagnosis of SLE. The author presents here the first case of fatal KFD simultaneously occurred with SLE complicated with hemophagocytic syndrome and severe infection. The recognition of this association is of significance for management of affected patients with early intensive immunosuppressive therapy for favorable outcome.

Keywords

Fatal Hemophagocytic syndrome Kikuchi–Fujimoto disease Lupus SLE 

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Copyright information

© Clinical Rheumatology 2008

Authors and Affiliations

  1. 1.Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of MedicineChulalongkorn University HospitalBangkokThailand

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