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Clinical Rheumatology

, Volume 26, Issue 7, pp 1195–1197 | Cite as

An unusual case of Candida tropicalis and Candida krusei arthritis in a patient with acute myelogenous leukemia before chemotherapy

  • Hon-Pin Wang
  • Yung-Feng Yen
  • Wei-Sheng Chen
  • Yuh-Lan Chou
  • Chang-Youh Tsai
  • Hsiao-Ning Chang
  • Chung-Tei ChouEmail author
Case Report

Abstract

A 79-year-old male with acute myelogenous leukemia developed acute right knee arthritis during admission, after the use of broad-spectrum antibiotics before chemotherapy. The initial synovial fluid sample appeared to be mildly inflammatory with a low white cell count. The fungal septic arthritis was not diagnosed until Candida tropicalis, a rare species of Candida, was isolated in the synovial fluid. Although fluconazole is effective in treating the microorganism, the untreated leukemia rendered the infection incurable and led to the growth of fluconazole-resistant Candida krusei. We reported the unusual case of fungal arthritis and reviewed the literature.

Keywords

Acute myelogenous leukemia Candida krusei Candida tropicalis Septic arthritis 

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Copyright information

© Clinical Rheumatology 2006

Authors and Affiliations

  • Hon-Pin Wang
    • 1
  • Yung-Feng Yen
    • 2
  • Wei-Sheng Chen
    • 1
  • Yuh-Lan Chou
    • 3
  • Chang-Youh Tsai
    • 1
    • 4
  • Hsiao-Ning Chang
    • 1
    • 4
  • Chung-Tei Chou
    • 1
    • 4
    Email author
  1. 1.Division of Allergy, Immunology, and Rheumatology, Department of MedicineTaipei Veterans General HospitalTaipeiRepublic of China
  2. 2.Division of Infectious DiseasesTaipei Veterans General HospitalTaipeiRepublic of China
  3. 3.Department of MedicineTaipei Veterans General HospitalTaipeiRepublic of China
  4. 4.Department of MedicineNational Yang-Ming University School of MedicineTaipei CityRepublic of China

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