Clinical Rheumatology

, Volume 25, Issue 5, pp 764–765 | Cite as

Polymyalgia rheumatica and colon malignacy: case report

Case Report


Polymyalgia rheumatica (PMR) is a relatively common disorder in the elderly. Whereas the relationship between polymyalgia rheumatica and giant cell arteritis (GCA) is well recognized, there is still controversy about PMR and malignancy. We are presenting a patient with PMR and adenocarcinoma of the sygmoid colon and hypothesize a paraneoplastic relationship.


Colon cancer Paraneoplastic syndrome Polymyalgia rheumatica 


  1. 1.
    Hazleman BL (2000) Polymyalgia rheumatica and giant cell arteritis. In: Klippel JH, Dieppe PA (eds) Rheumatology, 2nd edn. Mosby, London, pp. 7/21.1–7/21.8Google Scholar
  2. 2.
    Spiera R, Spiera H (2004) Inflammatory diseases in older adults: polymyalgia rheumatica. Geriatrics 59:39–43PubMedGoogle Scholar
  3. 3.
    Bird HA, Esselinckx A, Dixon AstJ, Mowat AG, Wood PHN (1979) An evaluation of criteria for polymyalgia rheumatica. Ann Rheum Dis 38: 434–439PubMedCrossRefGoogle Scholar
  4. 4.
    Chuang TY, Hunder GG, Ilstrup DM, Kurland LT (1982) Polymyalgia rheumatica: a ten year epidemiologic study. Ann Intern Med 97:672–680PubMedGoogle Scholar
  5. 5.
    Bird HA, Leeb BF, Montecucco CM, Misiunienne, Nesher G, Pai S, Pease C, Rovensky J, Rozman B (2005) A comparison of the sensitivity of diagnostic criteria for polymyalgia rheumatica. Ann Rheum Dis 64:626–629CrossRefPubMedGoogle Scholar
  6. 6.
    Leeb BF, Bird HA, Nesher G et al (2003) EULAR resoponse criteria for polymyalgia rheumatica: results of an initiative of the European collaborating polymyalgia rheumatica group (subcommittee of ESCISIT). Ann Rheum Dis 62:1189–1194CrossRefPubMedGoogle Scholar
  7. 7.
    Salvarani C, Cantini F, Boiardi L, Hunder GG (2004) Polymyalgia rheumatica. Best Pract Res Clin Rheumatol 18:705–722CrossRefPubMedGoogle Scholar
  8. 8.
    Nuti R, Giordano N, Martini G et al (2005) Is polymialgia rheumatica caused by infectious agents? J Rheumatol 32:200–201PubMedGoogle Scholar
  9. 9.
    Salvarani C, Boiardi L, Mantovani V et al (1999) HLA-DRB1 alleles associated with polymyalgia rheumatica in northern Italy: correlation with disease severity. Ann Rheum Dis 58:300–308CrossRefGoogle Scholar
  10. 10.
    Uddhammar A, Sojka BN, Rantapaa-Dahlqvist S (1996) HLA antigens in polymyalgia rheumatica in northern Sweden. Clin Rheumatol 15:486–490CrossRefPubMedGoogle Scholar
  11. 11.
    Martinez-Tabod VM, Bartolome MJ, Lopez-Hoyos M, et al (2004) HLADRB1 allele distribution in polymyalgia rheumatica and giant cell arteritis: influence on clinical subgroups and prognosis. Semin Arthritis Rheum 34:454–464CrossRefPubMedGoogle Scholar
  12. 12.
    Chakravarty E, Genovese MC (2003) Rheumatic syndromes associated with malignancy. Curr Opin Rheumatol 15:35–43CrossRefPubMedGoogle Scholar
  13. 13.
    Sidhom OA, Basalaev M, Sigal LH (1993) Renal cell carcinoma presenting as polymyalgia rheumatica. Arch Intern Med 153:2043–2045CrossRefPubMedGoogle Scholar
  14. 14.
    Kane I, Menon S (2003) Carcinoma of the prostate presenting as polymyalgia rheumatica. Rheumatology 42:385–387CrossRefPubMedGoogle Scholar
  15. 15.
    Martin WG, Potyk DK (2004) Polymyalgia rheumatica: can the diagnosis be made in the presence of malignancy? J Am Geriatr Soc 52:1028–1030CrossRefPubMedGoogle Scholar
  16. 16.
    Anton E (2005) Polymyalgia rheumatica and malignancy: the question remains open. J Am Geriatr Soc 53:355–356CrossRefPubMedGoogle Scholar
  17. 17.
    Naschitz JE (2001) Rheumatic syndromes: clues to occult neoplasia. Curr Opin Rheumatol 13:62–66CrossRefPubMedGoogle Scholar

Copyright information

© Clinical Rheumatology 2005

Authors and Affiliations

  1. 1.Hospital for cardial, pulmonal and rheumatic rehabilitationOpatijaCroatia
  2. 2.Department of RheumatologyClinical Hospital Center ZagrebZagrebCroatia

Personalised recommendations