Clinical Rheumatology

, 25:542 | Cite as

Anti-topoisomerase I antibodies in systemic lupus erythematosus as a marker of severe nephritis

  • Mohamed A. Hamidou
  • Marie A. Audrain
  • Agathe Masseau
  • Christian Agard
  • Anne Moreau
Brief Report

Abstract

The authors report nine patients with systemic lupus erythematosus associated with anti-topoisomerase I antibodies (ELISA test) without features of systemic sclerosis. These antibodies were correlated with the disease activity and might be a marker of the severity of the closely related to difusse proliferative glomerulonephritis.

Keywords

Anti-topoisomerase I antibodies Systemic lupus erythematosus Systemic sclerosis 

References

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Copyright information

© Clinical Rheumatology 2006

Authors and Affiliations

  • Mohamed A. Hamidou
    • 1
  • Marie A. Audrain
    • 2
  • Agathe Masseau
    • 1
  • Christian Agard
    • 1
  • Anne Moreau
    • 3
  1. 1.Department of Internal MedicineUniversity Hospital Hôtel-DieuNantesFrance
  2. 2.Laboratory of ImmunologyUniversity Hospital Hôtel-DieuNantesFrance
  3. 3.Laboratory of PathologyUniversity Hospital Hôtel-DieuNantesFrance

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