Anti-topoisomerase I antibodies in systemic lupus erythematosus as a marker of severe nephritis
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The authors report nine patients with systemic lupus erythematosus associated with anti-topoisomerase I antibodies (ELISA test) without features of systemic sclerosis. These antibodies were correlated with the disease activity and might be a marker of the severity of the closely related to difusse proliferative glomerulonephritis.
KeywordsAnti-topoisomerase I antibodies Systemic lupus erythematosus Systemic sclerosis