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Clinical Rheumatology

, Volume 24, Issue 6, pp 652–654 | Cite as

Unusual association of systemic sclerosis and ankylosing spondylitis

  • Cinira S. Soledade
  • Percival D. Sampaio-Barros
  • Adil M. Samara
  • João Francisco Marques-Neto
Letter

Systemic sclerosis (SSc) and ankylosing spondylitis (AS) are diseases that present distinct epidemiologic patterns [1, 2]. Since apparently no physiopathologic link exists between them, the chances of these two infrequent diseases occurring in the same patient are remote. In a review of the literature only four reports were found. The first one reported a patient with a long-standing untreated AS who presented with a malignant lymphoma and simultaneously developed SSc [3]. The second was a report of a patient with a combination of scleroderma and AS, whose presenting complaint was transfer dysphagia due to impaired relaxation of the upper esophageal sphincter as a result of tight overlying cervical skin or sclerodermatous involvement of the sphincter itself [4]. The third described a 40-year-old patient with a diagnosis of spondyloarthropathy associated with the CREST (calcinosis, Raynaud’s phenomenon, esophageal dysfunction, sclerodactyly, telangiectasia) syndrome [5]. A description...

Keywords

Ankylose Spondylitis Interstitial Lung Disease Force Vital Capacity Pulmonary Involvement Idiopathic Inflammatory Myopathy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Clinical Rheumatology 2004

Authors and Affiliations

  • Cinira S. Soledade
    • 1
  • Percival D. Sampaio-Barros
    • 1
  • Adil M. Samara
    • 1
  • João Francisco Marques-Neto
    • 1
  1. 1.Rheumatology Unit, Department of Internal MedicineState University of Campinas Faculty of Medical Sciences (UNICAMP)CampinasBrazil

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