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Molecules and Cells

, Volume 31, Issue 6, pp 491–496 | Cite as

The coded functions of noncoding RNAs for gene regulation

  • Sojin An
  • Ji-Joon SongEmail author
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Abstract

For eukaryotes, fine tuning of gene expression is necessary to coordinate complex genetic information. Recent studies have shown that noncoding RNAs (ncRNAs) play central roles in this process. For example, ncRNAs participate in multiple diverse functions such as mRNA degradation, epigenetic regulation and alternative splicing. The findings regarding this new player in gene regulation suggest that the mechanism of gene regulation is much more complicated and subtle than previously thought. In this review, new findings concerning the role of ncRNAs in gene regulation are discussed.

Keywords

chromatin gene regulation RNA 

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Copyright information

© The Korean Society for Molecular and Cellular Biology and Springer Netherlands 2011

Authors and Affiliations

  1. 1.Structural Biology Laboratory of Epigenetics, Department of Biological Sciences, Graduate School of Nanoscience and Technology (World Class University)KI Institute for the BioCentury, Korea Advanced Institute of Science and TechnologyDaejeonKorea

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