Oxygen consumption rate for evaluation of COQ2 variants associated with multiple system atrophy

  • Tsutomu YasudaEmail author
  • Takashi Matsukawa
  • Jun Mitsui
  • Shoji TsujiEmail author
Letter to Editor


Funding information

Jun Mitsui is funded by JSPS KAKENHI Grant Numbers 25860700 and 15K09334. Shoji Tsuji is funded by KAKENHI (Grants-in-Aid for Scientific Research on Innovative Areas Nos. 22129001 and 22129002) from the Ministry of Education, Culture, Sports, Science and Technology of Japan, and Grants-in-Aid [H23-Jitsuyoka (Nanbyo)-Ippan-004 and H26-Jitsuyoka (Nanbyo)-Ippan-080] from the Ministry of Health, Welfare and Labour, Japan, and grants (Nos. 15ek0109065h0002, 16kk0205001h001, 17kk0205001h0002, and 17ek0109279h0001) from the Japan Agency for Medical Research and Development (AMED).


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    The Multiple-System Atrophy Research Collaboration (2013) Mutations in COQ2 in familial and sporadic multiple-system atrophy. N Engl J Med 369(3):233–244CrossRefGoogle Scholar
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    Zhao Q, Yang X, Tian S, An R, Zheng J, Xu Y (2016) Association of the COQ2 V393A variant with risk of multiple system atrophy in East Asians: a case-control study and meta-analysis of the literature. Neurol Sci 37:423–430CrossRefGoogle Scholar
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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Neurology, Graduate School of MedicineThe University of TokyoTokyoJapan
  2. 2.Department of Molecular Neurology, Graduate School of MedicineThe University of TokyoTokyoJapan
  3. 3.International University of Health and WelfareNarita-shiJapan

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