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Journal of Artificial Organs

, Volume 22, Issue 4, pp 276–285 | Cite as

Mathematical evaluation of cardiac beat synchronization control used for a rotary blood pump

  • Daisuke OgawaEmail author
  • Shinji Kobayashi
  • Kenji Yamazaki
  • Tadashi Motomura
  • Takashi Nishimura
  • Junichi Shimamura
  • Tomonori Tsukiya
  • Toshihide Mizuno
  • Yoshiaki Takewa
  • Eisuke Tatsumi
Original Article Artificial Heart (Basic)
  • 118 Downloads

Abstract

We studied a control method of rotary blood pumps (RBPs), which is called as the cardiac beat synchronization (CBS) system. Usually, RBPs operate at constant target rotational speed, meanwhile, the CBS system modulates target speed synchronizing with cardiac beat. We built a computer simulation method to evaluate the CBS system. This simulator acquires a mathematical model of a circulatory system including a RBP and can provide us the theoretical hemodynamics when our control method is applied. We compared theoretical results with experimental ones with the model focusing on both pulsatility and aortic valve (AV) opening interval enhanced by the CBS system. Our simulator could reproduce behavior of the circulatory system whether the RBP is connected or not. Comparison among no RBP, constant assist, systolic assist, and diastolic assist modes indicated that pulsatility is enhanced with systolic assist theoretically. While systolic assist decreased AV opening interval, diastolic assist made it longer than the ones in other control strategies.

Keywords

Rotary blood pump Synchronization with cardiac beat Pulsatility Simulation 

Notes

Compliance with ethical standards

Conflict of interest

D. Ogawa and S. Kobayashi are employed by Sun medical Technology Research Corp. K. Yamazaki serves as a consultant to Sun medical Technology Research Corp. T. Motomura is employed by Evaheart, Inc. Other authors declare that there is no conflict of interest.

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Copyright information

© The Japanese Society for Artificial Organs 2019

Authors and Affiliations

  • Daisuke Ogawa
    • 1
    Email author
  • Shinji Kobayashi
    • 1
  • Kenji Yamazaki
    • 2
  • Tadashi Motomura
    • 3
  • Takashi Nishimura
    • 4
  • Junichi Shimamura
    • 5
  • Tomonori Tsukiya
    • 5
  • Toshihide Mizuno
    • 5
  • Yoshiaki Takewa
    • 5
  • Eisuke Tatsumi
    • 5
  1. 1.Sun Medical Technology Research Corp.Suwa-cityJapan
  2. 2.Hokkaido Cardiovascular HospitalSapporoJapan
  3. 3.Evaheart Inc.HoustonUSA
  4. 4.Department of Cardiac SurgeryTokyo Metropolitan Geriatric HospitalTokyoJapan
  5. 5.Department of Artificial OrgansNational Cerebral and Cardiovascular Center Research InstituteSuita, OsakaJapan

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