Combination of ECMO and cytokine adsorption therapy for severe sepsis with cardiogenic shock and ARDS due to Panton–Valentine leukocidin—positive Staphylococcus aureus pneumonia and H1N1
Sepsis-induced cardiogenic shock in combination with severe acute respiratory failure represents a life-threatening combination that is often refractory to the conventional methods of treatment. We describe the case of a 33-year-old patient who developed acute cardiovascular collapse and ARDS secondary to superinfection of Panton–Valentine leukocidin—positive Staphylococcus aureus and H1N1 pneumonia who underwent successful combination therapy for severe sepsis-related cardiomyopathy and respiratory failure using extracorporeal membrane oxygenation and cytokine adsorption therapy.
KeywordsExtracorporeal membrane oxygenation (ECMO) Sepsis Cytokines Adsorption therapy H1N1
The Cytosorb device was purchased from Linc Medical, Leicestershire, UK; representatives of whom have also been involved in educating staff.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no competing interests.
- 8.Maclaren G, Butt W. Extracorporeal membrane oxygenation and sepsis. Critical care and resuscitation J Australas Acad Cri Care Med. 2007;9:76–80.Google Scholar
- 17.Bracht H, Schneider EM, Weiss M, Hohmann H, Georgieff M, Barth E. Pattern of cytokine removal using an adsorption column CytoSorb during severe Candida albicans induced septic shock. Infection. 2013;41:S1–90.Google Scholar