Journal of Artificial Organs

, 11:171 | Cite as

Clinical application of artificial bone in the maxillofacial region

  • Hideto SaijoEmail author
  • Ung-il Chung
  • Kazuyo Igawa
  • Yoshiyuki Mori
  • Daichi Chikazu
  • Mitsuyoshi Iino
  • Tsuyoshi Takato
Review Paper


Hard tissue reconstruction is very useful for bony defects of the maxillofacial region. Autogenous bone, allogeneic bone, and artificial bone have been used to reconstruct maxillofacial bone; however, the use of autogenous bone involves high surgical invasiveness because of the need to harvest the bone. The use of allogeneic bone is associated with infections, raises ethical concerns, and is not widely used in Japan. Artificial bone has several advantages, including no need for bone harvesting, excellent biocompatibility, and a relatively easy surgical procedure. Use of artificial bone avoids the much greater invasiveness of harvesting bone, and several types of artificial bone have been developed. Design requirements for artificial bone include surgical manipulability, structural compatibility with the defective area, support properties, and the ability to induce bone regeneration; however, no artificial bone meeting all these requirements has yet been developed. Artificial bone is used in many patients in our medical center, and we have been active in developing the next generation of artificial bone with better properties. In this article, we present a case history and discuss the future development of artificial bone for use in maxillofacial reconstruction.

Key words

Custom-made artificial bone Maxillofacial reconstruction 3D model 


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Copyright information

© The Japanese Society for Artificial Organs 2008

Authors and Affiliations

  • Hideto Saijo
    • 1
    Email author
  • Ung-il Chung
    • 2
  • Kazuyo Igawa
    • 1
  • Yoshiyuki Mori
    • 1
  • Daichi Chikazu
    • 1
  • Mitsuyoshi Iino
    • 1
  • Tsuyoshi Takato
    • 1
  1. 1.Department of Oral and Maxillofacial Surgery, Faculty of MedicineThe University of TokyoTokyoJapan
  2. 2.Division of Tissue Engineering, Faculty of MedicineThe University of Tokyo HospitalTokyoJapan

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