Conservative treatment of infected mesh by use of gentamycin impregnated calcium sulphate antibiotic beads: a report of two cases
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Reinforcing an abdominal wall hernia repair with permanent mesh reduces the risk of recurrence . However, mesh infection can occur in up to 5% of implants . This devastating complication may require prolonged hospitalization and systemic antibiotics, repeat interventions to drain sepsis and ultimately mesh explantation. Compared to primary repair, the latter is typically a difficult operation in a hostile abdomen with higher risk of morbidity including bowel injury and subsequent enteric fistulae, bleeding, wound dehiscence and hernia recurrence. Consequently, it is desirable to salvage the mesh by non-operative means. Large studies investigating the optimal method of mesh salvage are lacking and methods to manage mesh infection are mainly derived from case studies. Typically, drainage of the associated infection with prolonged systemic antibiotics are the mainstay, but other therapies such as V.A.C.® (KCI Inc., San Antonio, TX) negative pressure wound therapy...
Compliance with ethical standards
Conflict of interest
None of the authors have any conflict of interest to declare.
Ethical approval is not required for this type of study.
Statement on human and animal rights
All procedures performed in this study involving human participants were in accordance with the ethical standards of the institution and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Experiments with laboratory animals were not included in this study.
Both individuals who participated in this study provided informed consent for the off label use of antibiotic-impregnated calcium sulphate beads and for the use of their information as part of this case report.
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