Pediatric and Developmental Pathology

, Volume 7, Issue 5, pp 546–548

Dysmorphic Villi Mimicking Partial Mole in a Case with del(18)(q21)

  • Dinesh Rakheja
  • Kathleen S. Wilson
  • Beverly B. Rogers
Case Reports
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Abstract

In this article, we report the histopathologic findings in a placenta from an early second trimester abortion. The placental villi showed prominent scalloping with many intravillous trophoblastic pseudoinclusions and mild trophoblastic hyperplasia, mimicking the morphology of partial hydatidiform mole. The placental karyotype was 46,XY,del(18)(q21). These histopathologic changes have been previously described in numerical chromosomal aberrations like triploidy, tetraploidy, and trisomies, but not in structural chromosomal abnormalities.

Keywords

dysmorphic villi partial hydatidiform mole chromosomal deletion 

Copyright information

© Society of Pediatric Pathology 2004

Authors and Affiliations

  • Dinesh Rakheja
    • 1
  • Kathleen S. Wilson
    • 2
  • Beverly B. Rogers
    • 1
  1. 1.Department of PathologyChildren’s Medical Center of DallasDallasUSA
  2. 2.Department of PathologyUniversity of Texas Southwestern Medical CenterDallasUSA

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