Pediatric and Developmental Pathology

, Volume 6, Issue 5, pp 464–466 | Cite as

Adrenocortical and Hepatic Nodules within Placental Tissue

  • Suzanne M. JacquesEmail author
  • Faisal Qureshi
Letter to the Editor

Adrenocortical and hepatic nodules have only rarely been described within placental tissue [1 , 2, 3, 4, 5, 6, 7, 8, 9]. The adrenal nodules have been termed heterotopias, while the hepatic nodules have been termed adenomas or adenoma-like, but the histogenesis remains unclear [1, 2, 3, 4, 5, 6, 7, 8, 9]. We have previously reported two cases of microscopic placental adrenocortical nodules [4]. Since that time, we have seen three additional cases of placental adrenocortical nodules, as well as three placental hepatic nodules. In each case, the nodules were a microscopic finding and most likely not related to the pregnancy outcome or presence of fetal disease. Because these lesions are frequently microscopic and discovered only incidentally, they may be far more common than reported.

The adrenocortical nodules were found in third trimester placentas. The mothers ranged in age from 22 to 34 years. One mother delivered at 33 wk gestational age, and the placenta had no other significant...


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Copyright information

© Society for Pediatric Pathology 2003

Authors and Affiliations

  1. 1.Department of PathologyHarper University Hospital, Wayne State University School of Medicine, Detroit, MIUSA

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