Advertisement

Pediatric and Developmental Pathology

, Volume 6, Issue 5, pp 464–466 | Cite as

Adrenocortical and Hepatic Nodules within Placental Tissue

  • Suzanne M. JacquesEmail author
  • Faisal Qureshi
Letter to the Editor

Adrenocortical and hepatic nodules have only rarely been described within placental tissue [1 , 2, 3, 4, 5, 6, 7, 8, 9]. The adrenal nodules have been termed heterotopias, while the hepatic nodules have been termed adenomas or adenoma-like, but the histogenesis remains unclear [1, 2, 3, 4, 5, 6, 7, 8, 9]. We have previously reported two cases of microscopic placental adrenocortical nodules [4]. Since that time, we have seen three additional cases of placental adrenocortical nodules, as well as three placental hepatic nodules. In each case, the nodules were a microscopic finding and most likely not related to the pregnancy outcome or presence of fetal disease. Because these lesions are frequently microscopic and discovered only incidentally, they may be far more common than reported.

The adrenocortical nodules were found in third trimester placentas. The mothers ranged in age from 22 to 34 years. One mother delivered at 33 wk gestational age, and the placenta had no other significant...

References

  1. 1.
    Cox, JN, Chavrier, F 1980Heterotopic adrenocortical tissue within a placentaPlacenta1131133PubMedGoogle Scholar
  2. 2.
    Labarrere, CA, Caccamo, D, Telenta, M, Althabe, O, Gutman, R 1984A nodule of adrenocortical tissue within a human placenta: light microscopic and immunocytochemical findingsPlacenta5139143PubMedGoogle Scholar
  3. 3.
    Kraft, K 1984Akzessorisches Nebennierenrindengewebe in der PlazentaZ Geburtshilfe Perinatol188191193PubMedGoogle Scholar
  4. 4.
    Qureshi, F, Jacques, SM 1995Adrenocortical heterotopia in the placentaPediatr. Pathol. Lab. Med.155156PubMedGoogle Scholar
  5. 5.
    Vogel, M 1996Atlas der Morphologischen Plazentadiagnostik 2nd edition, SpringerNew York7980Google Scholar
  6. 6.
    Guschmann, M, Vogel, M, Urban, M 2000Adrenal tissue in the placenta: a heterotopia caused by migration and embolism?Placenta21427431CrossRefPubMedGoogle Scholar
  7. 7.
    Chen, KTK, Chan, KM, Kassel, SH 1986Hepatocellular adenoma of the placentaAm. J. Surg. Pathol.10436440PubMedGoogle Scholar
  8. 8.
    Vesoulis, Z, Agamanolis, D 1998Benign hepatocellular tumor of the placentaAm. J. Surg. Pathol.22355359CrossRefPubMedGoogle Scholar
  9. 9.
    Khalifa, MA, Gersell, DJ, Hansen, CH, Lage, JM 1998Hepatic (hepatocellular) adenoma of the placenta: a study of four casesInt. J. Gynecol. Pathol.17241244PubMedGoogle Scholar

Copyright information

© Society for Pediatric Pathology 2003

Authors and Affiliations

  1. 1.Department of PathologyHarper University Hospital, Wayne State University School of Medicine, Detroit, MIUSA

Personalised recommendations