Journal of Solid State Electrochemistry

, Volume 16, Issue 9, pp 2907–2911 | Cite as

Efficient electrocatalytic oxidation and selective determination of isoniazid by Fe(tmphen) 3 2+ -exchanged Nafion®-modified electrode

Original Paper

Abstract

Cyclic voltammetry and electrochemical impedance studies of Fe(tmphen) 3 2+ (where tmphen = 3,4,7,8-tetramethyl-1,10-phenanthroline)-immobilized Nafion®-modified glassy carbon electrode (GC/Nf/Fe(tmphen) 3 2+ ) are carried out in 0.1 M Na2SO4 solution. Nafion–Fe(tmphen) 3 2+ complex exhibits efficient electrocatalytic oxidation of isoniazid. The linear double reciprocal plot of current and concentration of isoniazid shows a Michaelis–Menten-type catalytic process. The catalytic oxidation currents are proportional to the concentration of isoniazid and show a wide linear calibration range for the quantitative determination of isoniazid. Detection limit and sensitivity are found to be 13 μM and 2.5 μA mM−1, respectively.

Keywords

Nafion® Electrocatalysis Isoniazid oxidation Fe(tmphen)32+ 

Notes

Acknowledgments

Generous funding from DST and CSIR, New Delhi is gratefully acknowledged. We acknowledge Dr. S. Abraham John, Gandhigram Rural University, India, for fruitful discussions. One of the authors, UPA, acknowledges CSIR for SRF.

Supplementary material

10008_2012_1724_MOESM1_ESM.pdf (16 kb)
ESM 1 (PDF 16 kb)

References

  1. 1.
    Madan J, Dwivedi AK, Singh S (2005) Anal Chim Acta 538:345–353CrossRefGoogle Scholar
  2. 2.
    Nagaraja P, Murthy KCS, Yathirajan HS (1996) Talanta 43:1075–1080CrossRefGoogle Scholar
  3. 3.
    Khuhawar MY, Rind FMA (2002) J Chromatogr B 766:357–363CrossRefGoogle Scholar
  4. 4.
    Liu J, Zhou W, You T, Fenglei L, Wang E, Dong S (1996) Anal Chem 68:3350–3353CrossRefGoogle Scholar
  5. 5.
    Goicoechea HC, Olivieri AC (1999) J Pharm Biomed Anal 20:681–686CrossRefGoogle Scholar
  6. 6.
    Lapa RAS, Lima JLFC, Santos JLM (2000) Anal Chim Acta 419:17–23CrossRefGoogle Scholar
  7. 7.
    Zheng XW, Zhang ZJ (1999) Analyst 124:763–766CrossRefGoogle Scholar
  8. 8.
    Gao Z-N, Han X-X, Yao H-Q, Liang B, Liu W-Y (2006) Anal Bioanal Chem 385:1324–1329CrossRefGoogle Scholar
  9. 9.
    Majidi MR, Jouyban A, Asadpour-Zeynali K (2006) J Electroanal Chem 589:32–37CrossRefGoogle Scholar
  10. 10.
    Yang G, Wang C, Zhang R, Wang C, Qu Q, Hu X (2008) Bioelectrochemistry 73:37–42CrossRefGoogle Scholar
  11. 11.
    Bergamini MF, Santos DP, Zanoni MVB (2010) Bioelectrochemistry 77:133–138CrossRefGoogle Scholar
  12. 12.
    Jena BK, Raj CR (2010) Talanta 80:1653–1656CrossRefGoogle Scholar
  13. 13.
    Kalimuthu P, John SA (2009) Electrochem Commun 11:1065–1068CrossRefGoogle Scholar
  14. 14.
    Johnsson K, Schultz PG (1994) J Am Chem Soc 116:7425–7426CrossRefGoogle Scholar
  15. 15.
    Hillar A, Loewen PC (1995) Arch Biochem Biophys 323:438–446CrossRefGoogle Scholar
  16. 16.
    Harmer MA, Farneth WE, Sun Q (1996) J Am Chem Soc 118:7708–7715CrossRefGoogle Scholar
  17. 17.
    Ford-Smit MH, Sutin N (1961) J Am Chem Soc 83:1830–1834CrossRefGoogle Scholar
  18. 18.
    Ganesan V, John SA, Ramaraj R (2001) J Electroanal Chem 502:167–173CrossRefGoogle Scholar
  19. 19.
    Azad UP, Ganesan V (2010) Chem Commun 46:6156–6158CrossRefGoogle Scholar
  20. 20.
    Martin CR, Rubinstein I, Bard AJ (1982) J Am Chem Soc 104:4817–4824CrossRefGoogle Scholar
  21. 21.
    Asadpour-Zeynali K, Soheili-Azad P (2010) Electrochim Acta 55:6570–6576CrossRefGoogle Scholar
  22. 22.
    Shahrokhian S, Asadian E (2010) Electrochim Acta 55:666–672CrossRefGoogle Scholar
  23. 23.
    Karimi MA, Hatefi-Mehrjardi A, Mazloum-Ardakani M, Behjatmanesh-Ardakani R, Mashhadizadeh MH, Sargazi S (2010) Int J Electrochem Sci 5:1634–1648Google Scholar
  24. 24.
    Yan X, Bo X, Guo L (2011) Sensors Actuators B 155:837–842CrossRefGoogle Scholar
  25. 25.
    Raj CR, Chakraborty S (2006) Biosens Bioelectron 22:700–706CrossRefGoogle Scholar
  26. 26.
    Wang Q, Lu G, Yang B (2004) Biosens Bioelectron 19:1269–1275CrossRefGoogle Scholar
  27. 27.
    Frank MS, Rao PVK (1979) Indian J Chem 17A:632–634Google Scholar
  28. 28.
    Yi Q, Yu W (2009) J Electroanal Chem 633:159–164CrossRefGoogle Scholar
  29. 29.
    Cao R-G, Zhu B, Li J, Xu D (2009) Electrochem Commun 11:1815–1818CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Department of Chemistry, Faculty of ScienceBanaras Hindu UniversityVaranasiIndia

Personalised recommendations