Oral and Maxillofacial Surgery

, Volume 23, Issue 4, pp 481–486 | Cite as

Factors related to patients’ nutritional state after orthognathic surgery

  • Kazuhiro OoiEmail author
  • Nobuo Inoue
  • Kazuhiro Matsushita
  • Hiro-o Yamaguchi
  • Tadashi Mikoya
  • Shuichi Kawashiri
  • Kanchu Tei
Original Article



The purpose of this study was to evaluate patients’ nutritional state after orthognathic surgery.


The subjects were 40 female patients with dentofacial deformity aged 17–33 years who were undergoing bilateral sagittal splitting ramus osteotomy. Twenty patients were treated with intermaxillary fixation, and 20 patients were treated without intermaxillary fixation. Age and body mass index (kg/m2) were assessed as physical factors, operation time, blood loss, and amount of mandibular movement with or without intermaxillary fixation were assessed as operation stress factors, and the following laboratory data, total protein, serum albumin, total cholesterol, total lymphocytes, and cholinesterase were assessed as nutritional state factors at 1 and 2 weeks after surgery. Statistical analysis was performed for body weight loss and relationship between body weight loss and examination factors.


Body weight significantly decreased 2.3% at 1 week and 3.9% at 2 weeks after surgery rather than preoperation. All laboratory data except total lymphocyte were decreased at 1 week after surgery and still remained significantly decreased at 2 weeks after surgery. There was a statistically significant relationship between body weight loss at 1 week after surgery and operation time.


These results indicate that long operation time caused body weight loss in orthognathic surgery.


Postoperative nutritional state Orthognathic surgery Operation time 


Author contributions

K.O. and N.I. designed most of the experiments and wrote the main manuscript text and prepared all figures and tables. K.M. and H.Y. were the primary persons responsible for carrying out all experimental procedures. T.M. analyzed the data. S.K. and K.T. are the persons who made the final approval of the article.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Approval was given by the Hokkaido University Hospital Ethics Committee (Ref. No 010-0285).

Patient consent

All patients are informed about the research purpose and agree to use their clinical data for this study.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Kazuhiro Ooi
    • 1
    • 2
    Email author
  • Nobuo Inoue
    • 3
  • Kazuhiro Matsushita
    • 1
  • Hiro-o Yamaguchi
    • 1
  • Tadashi Mikoya
    • 1
  • Shuichi Kawashiri
    • 2
  • Kanchu Tei
    • 1
  1. 1.Oral and Maxillofacial Surgery, Department of Oral Patho-biological Science, Graduate School of Dental MedicineHokkaido UniversitySapporoJapan
  2. 2.Department of Oral and Maxillofacial Surgery, Graduate School of Medical ScienceKanazawa UniversityKanazawaJapan
  3. 3.Gerodontology, Department of Oral Health Science, Graduate School of Dental MedicineHokkaido UniversitySapporoJapan

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