Oral and Maxillofacial Surgery

, Volume 23, Issue 4, pp 493–497 | Cite as

Intraoral epidermoid cyst with extensive elastofibromatous changes: an unusual finding

  • Heitor Albergoni Silveira
  • Luciana Yamamoto Almeida
  • Matheus Henrique Lopes Dominguete
  • Kamila Prado Pereira Graciano
  • Andreia Bufalino
  • Jorge Esquiche LeónEmail author
Case Report



Epidermoid cysts (ECs) are rare and occur in the head and neck regions with an incidence from 1.6 to 7% of all cysts. In the oral cavity, approximately 80 ECs have been reported, representing less than 0.01% of all cysts.

Case report

We report a case of a 26-year-old man who developed a large EC in the midline floor of the mouth causing nodular swelling in the submental region and speech and swallowing difficulties. The lesion was surgically excised by intraoral approach and microscopically revealed an EC associated with extensive elastofibromatous changes in the cystic capsule.


Oral EC with extensive elastofibromatous changes is a finding extremely rare. The meaning of this finding is unknown, but a traumatic origin or deposit disorder of elastic fibers is suggested. To the best of our knowledge, intraoral EC with elastofibromatous changes has not been reported to date.


Epidermoid cyst Oral cyst Floor of the mouth Elastic tissue Elastofibromatous changes 



Jorge Esquiche León (2016/11419–0), Luciana Yamamoto Almeida (2016/02713-2) and Heitor Albergoni Silveira (2018/12734–2) have received research grants from the State of São Paulo Research Foundation.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Heitor Albergoni Silveira
    • 1
  • Luciana Yamamoto Almeida
    • 2
  • Matheus Henrique Lopes Dominguete
    • 3
  • Kamila Prado Pereira Graciano
    • 3
  • Andreia Bufalino
    • 1
  • Jorge Esquiche León
    • 4
    Email author
  1. 1.Oral Medicine, Department of Diagnosis and Surgery, Araraquara Dental SchoolSão Paulo State University (UNESP)AraraquaraBrazil
  2. 2.Department of Pathology and Forensic Medicine, Ribeirão Preto Medical School (FMRP/USP)University of São PauloSão PauloBrazil
  3. 3.Universidade Vale do Rio Verde (UninCor)Três CoraçõesBrazil
  4. 4.Oral Pathology, Department of Stomatology, Public Oral Health and Forensic Dentistry, Ribeirão Preto Dental SchoolUniversity of São Paulo (FORP/USP)Ribeirão PretoBrazil

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