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Non-ossifying fibroma (metaphyseal fibrous defect) of the mandible

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Abstract

A 15-year-old young man was referred for evaluation of a non-tender swelling of the left mandibular angle region. A non-ossifying fibroma was diagnosed. The lesion was enucleated under general anesthesia. The postoperative course was uneventful. There have been no signs of recurrence, and there was complete bone regeneration in the region 24 months after operation. This report also reviews other fifteen cases of non-ossifying fibroma in the mandible reported in the literature.

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References

  1. Marks KE, Bauer TW (1989) Fibrous tumors of bone. Orthop Clin North Am 20:377–393

    PubMed  CAS  Google Scholar 

  2. Park JK, Levy BA, Hanley JB (1982) Non-ossifying fibroma of the mandible: report of a case. J Baltim Coll Dent Surg 35:1–5

    CAS  Google Scholar 

  3. Estrada-Villasenor E, Delgado Cedillo EA, Rico Martinez G (2008) Prevalence of bone neoplasms in adolescents and young adults. Acta Ortop Mex 22:316–320

    PubMed  Google Scholar 

  4. Sontag LW, Pyle DI (1941) The appearance and nature of cyst-like areas in distal femoral metaphyses of children. Am J Roentgenol Radiat Ther 46:185–188

    Google Scholar 

  5. Jaffe HL, Lichtenstein L (1942) Non-osteogenic fibroma of bone. Am J Pathol 18:205–220

    PubMed  CAS  Google Scholar 

  6. Bailey JS, Nikitakis NG, Lopes M, Ord RA (2001) Nonossifying fibroma of the mandible in a 6-year-old girl: a case report and review of the literature. J Oral Maxillofac Surg 59:815–818

    Article  PubMed  CAS  Google Scholar 

  7. Hudson JW, Livesay KW, McCoy JM (2003) Condylar lesion. J Oral Maxillofac Surg 61:824–826

    Article  PubMed  CAS  Google Scholar 

  8. Rudy HN, Scheingold SS (1964) Solitary xanthogranuloma of the mandible. Report of a case. Oral Surg Oral Med Oral Pathol 18:262–271

    Article  PubMed  CAS  Google Scholar 

  9. Quinn JH, Graves LR, Leonard GI (1970) Unusual histiocytic lesion of the mandible: report of a case. J Oral Surg 28:528–530

    PubMed  CAS  Google Scholar 

  10. Liaw WJ, So TK, Yao YT (1979) Non ossifying fibroma of mandible. A case report. J Formos Med Assoc 78:795–802

    CAS  Google Scholar 

  11. Ide F, Kusuhara S, Onuma H, Miyake T, Umemura S (1982) Xanthic variant of the nonossifying fibroma (so called xanthofibroma) of the mandible: an ultrastructural study. Acta Pathol Jpn 32:135–142

    PubMed  CAS  Google Scholar 

  12. Mirra JM, Gold RH, Rand F (1982) Disseminated nonossifying fibromas in association with café-au-lait spots (Jaffe-Campanacci syndrome). Clin Orthop Relat Res 168:192–205

    PubMed  Google Scholar 

  13. Elzay RP, Mills S, Kay S (1984) Fibrous defect (non-ossifying fibroma) of the mandible. Oral Surg Oral Med Oral Pathol 58:402–407

    Article  PubMed  CAS  Google Scholar 

  14. Aldred MJ, Breckon JJW, Holland CS (1989) Non-osteogenic fibroma of the mandibular condyle. Br J Oral Maxillofac Surg 27:412–416

    Article  PubMed  CAS  Google Scholar 

  15. Uçkan S, Gürol M, Mutlu N, Güngör S (1999) Non-ossifying fibroma of the mandible: report of a case. Br J Oral Maxillofac Surg 37:152–154

    PubMed  Google Scholar 

  16. Makek M (1980) Non-ossifying fibroma of the mandible. A common lesion with unusual location. Arch Orthop Trauma Surg 96:225–227

    Article  PubMed  CAS  Google Scholar 

  17. Mizukawa N, Nishijima Y, Nishijima K (1997) Metaphyseal fibrous defect (nonossifying fibroma) in the mandible. A case report. Int J Oral Maxillofac Surg 26:129–130

    Article  PubMed  CAS  Google Scholar 

  18. Bessho K, Murakami K, Nishida M, Yokoe Y, Hyo Y, Iizuka T (1986) Nonossifying fibroma of the mandible: case report and review of literature. Jpn J Oral Maxillofac Surg 32:291–296

    Article  Google Scholar 

  19. Hatcher CH (1945) The pathogenesis of localized fibrous lesions in the metaphyses of long bones. Ann Surg 122:1016–1030

    Article  Google Scholar 

  20. Aegerter E, Kirkpatrick JA (1975) Orthopaedic diseases, 4th edn. Saunders, Philadelphia, p 314

    Google Scholar 

  21. Dahlin DC (1978) Bone tumours, 3rd edn. Thomas, Springfield, pp 122–136

    Google Scholar 

  22. Brassesco MS, Valera ET, Engel EE, Nogueira-Barbosa MH, Becker AP, Scrideli CA, Tone LG (2010) Clonal complex chromosome aberration in non-ossifying fibroma. Pediatr Blood Cancer 54:764–767

    PubMed  Google Scholar 

  23. Campanacci M, Laus M, Boriani S (1983) Multiple non-ossifying fibromata with extraskeletal anomalies: a new syndrome? J Bone Joint Surg Br 65:627–632

    PubMed  CAS  Google Scholar 

  24. Blau RA, Zwick DL, Westphal RA (1988) Multiple non-ossifying fibromas. A case report. J Bone Joint Surg Am 70:299–304

    PubMed  CAS  Google Scholar 

  25. Slootweg PJ (1989) Comparison of giant cell granuloma of the jaw and non-ossifying fibroma. J Oral Pathol Med 18:128–132

    Article  PubMed  CAS  Google Scholar 

  26. Lucas RB (1984) Pathology of tumours of the oral tissues, 4th edn. Churchill Livingstone, Edinburgh, pp 259–262

    Google Scholar 

  27. Fechner RE, Mills SE (1993) Tumor of bone and cartilage. Atlas of tumor pathology, 3rd series, fascicle 8. Armed Forces Institute of Pathology, Washington DC, pp 161–163

    Google Scholar 

  28. Fletcher CDM, Unni KK, Mertens F (2002) World Health Organization: classification of tumours. Pathology and genetics of tumours of soft tissue and bone. IARC Press, Lyon, pp 292–293

    Google Scholar 

  29. Clarke BE, Xipell JM, Thomas DP (1985) Benign fibrous histiocytoma of bone. Am J Surg Pathol 9:806–815

    Article  PubMed  CAS  Google Scholar 

  30. Kishino M, Murakami S, Toyosawa S, Nakatani A, Ogawa Y, Ishida T, Ijuhin N (2005) Benign fibrous histiocytoma of the mandible. J Oral Pathol Med 34:190–192

    Article  PubMed  Google Scholar 

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Acknowledgements

We would like to thank Dr. Kazuhisa Bessho for providing us his article.

We would like to thank Mr. Pedro Ernani Maciel.

Author information

Authors and Affiliations

  1. Av. Raja Gabaglia 1000/1209 Gutierrez, Belo Horizonte, MG-CEP 30441-070, Brazil

    Bruno Ramos Chrcanovic

  2. Rua Grão Mogol 386/304, Carmo, Belo Horizonte, MG-CEP 30310-010, Brazil

    Ana Luiza Albanese

  3. Department of Oral and Maxillofacial Surgery, School of Dentistry, Pontifícia Universidade Católica de Minas Gerais, Av. do Contorno 4747/1010, Serra, Belo Horizonte, MG-CEP 30110-921, Brazil

    Belini Freire-Maia

  4. Av. do Contorno 4747/loja 16, Serra, Belo Horizonte, MG-CEP 30110-921, Brazil

    Fernanda Cardoso Fonseca Nunes

  5. Laboratory of Oral Pathology, School of Dentistry, Pontifícia Universidade Católica de Minas Gerais, Av. Dom José Gaspar, 500 - Coração Eucarístico, Belo Horizonte, MG-CEP 30535-901, Brazil

    Paulo Eduardo Alencar Souza

  6. Department of Clinical Pathology and Dental Surgery, School of Dentistry, Universidade Federal de Minas Gerais, Av. Antonio Carlos, 6627, Pampulha, Belo Horizonte, MG-CEP 31270-901, Brazil

    Ricardo Santiago Gomez

Authors
  1. Bruno Ramos Chrcanovic
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  2. Ana Luiza Albanese
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  3. Belini Freire-Maia
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  4. Fernanda Cardoso Fonseca Nunes
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  5. Paulo Eduardo Alencar Souza
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  6. Ricardo Santiago Gomez
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Correspondence to Bruno Ramos Chrcanovic.

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Chrcanovic, B.R., Albanese, A.L., Freire-Maia, B. et al. Non-ossifying fibroma (metaphyseal fibrous defect) of the mandible. Oral Maxillofac Surg 15, 233–237 (2011). https://doi.org/10.1007/s10006-010-0244-7

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  • DOI: https://doi.org/10.1007/s10006-010-0244-7

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