Oral and Maxillofacial Surgery

, Volume 13, Issue 1, pp 45–48 | Cite as

Cystic clear cell myoepithelioma of the parotid gland. A case report

  • Hesna Muzeyyen Astarci
  • Asuman Celik
  • Nuran Sungu
  • Huseyin Ustun
Case Report



Myoepitheliomas of salivary glands are generally encapsulated, slowly growing asymptomic solid masses in which more than 50% are seen in the parotid gland. Cystic myoepitheliomas are very rare.

Case report

We present an 80-year-old man with a cystic mass in the right parotid gland that had undergone superficial parotidectomy. In gross examination, a mass containing a large cyst was observed. Microscopically, tumor consisted of clear cells and small cuboidal cells, forming tubules in a hyalinized stroma. Immunohistochemically, clear cells were immunoreactive for S100 and smooth muscle actin. Cuboidal cells were positive for cytokeratin. Diagnostic and differential diagnostic criteria were discussed under the light of the current literature.


Clear cell Myoepithelioma Epithelial–myoepithelial carcinoma Cystic 


  1. 1.
    Barnes L, Appel BN, Peres H et al (1985) Myoepithelioma of the head and neck: case reported review. J Surg Oncol 28(1):21–28PubMedCrossRefGoogle Scholar
  2. 2.
    Sciubba JJ, Brannon RB (1982) Myoepithelioma of salivary glands: report of 23 cases. Cancer 49(3):562–572PubMedCrossRefGoogle Scholar
  3. 3.
    Hansen T, Hilka MB (2004) Cystic myoepithelioma. A rare differential diagnosis of a cystic lesion of the parotid gland. HNO 52(11):1001–1003, 1005PubMedCrossRefGoogle Scholar
  4. 4.
    Alos L, Cardesa A, Bambi JA et al (1996) Myoepithelial tumors of salivary gland: a clinicopathologic, immunohistochemical, ultrastructural and flow-cytometric study. Semin Diagn Pathol 13(2):138–147PubMedGoogle Scholar
  5. 5.
    Ferri E, Pavon I, Armato E et al (2006) Myoepithelioma of a minor salivary gland of the cheek: case report. Acta Otorhinolaryngol Ital 26(1):43–46PubMedGoogle Scholar
  6. 6.
    Seifort G (1996) Classification and differential diagnosis of clear and basal cell tumors of the salivary gland. Semin Diagn Pathol 13:95–103Google Scholar
  7. 7.
    Kuwabara H, Uda H, Miyabe K, Seita K, Shibonushi T (1998) Malignant plasmacytoid myoepithelioma of the palate. Histological observations compared to benign predominant plasmacytoid myoepithelial cells in pleomorphic adenoma of the palate. Ultrastruct Pathol 22:153–160PubMedCrossRefGoogle Scholar
  8. 8.
    Luna MA, Batsakis JG, Ordonez NG, Mackey B, Tortoledo ME (1987) Salivary gland adenocarcinoma. Clinicopathologic analysis of three distinctive type. Semin Diagn Pathol 4:117–135PubMedGoogle Scholar
  9. 9.
    Wang B, Brandwein M (2002) Primary salivary clear cell tumors a diagnostic approach. Arch Pathol Lab Med 126:676–685PubMedGoogle Scholar
  10. 10.
    Seethala RR, Bernas EL, Hunt JL (2007) Epithelial myoepithelial carcinoma: a review of the clinicopathologic spectrum and immunophenotype characteristics in 61 tumors of the salivary gland upper aerodigestive tract. Am J Surg Pathol 31(1):44–57PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Hesna Muzeyyen Astarci
    • 1
  • Asuman Celik
    • 1
  • Nuran Sungu
    • 1
  • Huseyin Ustun
    • 1
  1. 1.Department of PathologyMinistry of Health, Ankara Training and Research HospitalAnkaraTurkey

Personalised recommendations