Medical Molecular Morphology

, Volume 40, Issue 1, pp 34–39 | Cite as

Ciliary ultrastructure in two sisters with Kartagener's syndrome

  • Kayoko Tanaka
  • Akihisa Sutani
  • Yuka Uchida
  • Yoshihiko Shimizu
  • Michio Shimizu
  • Masumi Akita
ORIGINAL PAPER

Abstract

Kartagener's syndrome (KS) is a clinical variant of primary ciliary dyskinesia involving situs inversus associated with chronic airway infections. We studied two sisters; the elder one had dextrocardia and scoliosis, and the younger one had situs inversus of the lung, liver, and stomach as well as dextrocardia. Both patients had chronic sinusitis and chronic bronchitis with bronchiectasis. In both cases, the ciliary defect associated with this syndrome is the absence of inner dynein arms.

Key words

Kartagener's syndrome Primary ciliary dyskinesia Situs inversus Dynein arm Electron microscopy 

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Copyright information

© The Japanese Society for Clinical Molecular Morphology 2007

Authors and Affiliations

  • Kayoko Tanaka
    • 1
  • Akihisa Sutani
    • 2
  • Yuka Uchida
    • 2
  • Yoshihiko Shimizu
    • 3
  • Michio Shimizu
    • 3
  • Masumi Akita
    • 1
  1. 1.Division of Morphological Science, Biomedical Research CenterSaitama Medical UniversitySaitamaJapan
  2. 2.Department of Respiratory MedicineSaitama Medical UniversitySaitamaJapan
  3. 3.Department of PathologySaitama Medical UniversitySaitamaJapan

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