, Volume 21, Issue 1, pp 15–26 | Cite as

“Hot” acetogenesis

  • Mirko Basen
  • Volker Müller
Special Feature: Review 11th International Congress on Extremophiles
Part of the following topical collections:
  1. 11th International Congress on Extremophiles


Thermophilic microorganisms as well as acetogenic bacteria are both considered ancient. Interestingly, only a few species of bacteria, all belonging to the family Thermoanaerobacteraceae, are described to conserve energy from acetate formation with hydrogen as electron donor and carbon dioxide as electron acceptor. This review reflects the metabolic differences between Moorella spp., Thermoanaerobacter kivui and Thermacetogenium phaeum, with focus on the biochemistry of autotrophic growth and energy conservation. The potential of these thermophilic acetogens for biotechnological applications is discussed briefly.


Acetogenesis Thermophiles Thermoanaerobacter kivui Moorella thermoacetica Thermacetogenium phaeum Wood-Ljungdahl pathway CODH/ACS 



Wood-Ljungdahl pathway


CO dehydrogenase/acetyl-CoA synthase




Energy converting hydrogenase



We would like to thank the Deutsche Forschungsgemeinschaft (DFG) for generous support.


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© Springer Japan 2016

Authors and Affiliations

  1. 1.Department of Molecular Microbiology and Bioenergetics, Institute of Molecular BiosciencesJohann Wolfgang Goethe UniversityFrankfurt Am MainGermany

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