Psychiatric comorbidities in autism spectrum disorders: findings from a Danish Historic Birth Cohort
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Several psychiatric comorbidities are common among patients with autism spectrum disorders (ASD) [1, 2]. In contrast, fewer studies have indicated lower rates of alcohol related disorders (ARD) and substance abuse in ASD patients [3, 4]. The aim of this brief report is to estimate the psychiatric comorbidity rates in ASD patients utilizing a Danish Historic Birth Cohort (HBC) which consists of maternal biologic samples of more than 1,00,000 pregnant women collected during their antenatal visits from 1980 to 2004 and kept at Statens Serum Institute in Copenhagen, Denmark .
Danish nation-wide health registers were utilized to follow-up individuals in the HBC until September 2009. All singleton ASD cases born between 1982 and 2000 in the HBC were identified based on the ICD-8 codes 299.xx up to 1993, and ICD-10 codes DF84.xxsince 1994. Controls were non-ASD singleton individuals in the HBC frequency-matched with cases on gender and year of birth. All psychiatric...
KeywordsAutism Spectrum Disorder Autism Spectrum Disorder Attention Deficit Hyperactivity Disorder Attention Deficit Hyperactivity Disorder Psychiatric Comorbidities
The Danish Historic Birth Cohort was established at Statens Serum Institute, Copenhagen with a grant from The Danish Medical Research Foundation and The Danish Ministry of the Interior and Health (Project no 271-05-0523/09-060179). This study is funded by Aarhus University Faculty of Health Sciences, Aarhus, Denmark and Statens Serum Institute, Department of Clinical Biochemistry and Immunology, Copenhagen, Denmark (Project title: Intrauterine exposures and childhood psychiatric disorders, Project ID: 494028). The authors thank Vibeke Munk from Copenhagen University for her administrative assistance.
Conflict of interest
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