European Child & Adolescent Psychiatry

, Volume 15, Supplement 1, pp i38–i45

Factors related to Health-Related Quality of Life (HRQoL) among children with ADHD in Europe at entry into treatment

  • Anne W. Riley
  • Georg Spiel
  • David Coghill
  • Manfred Döpfner
  • Bruno Falissard
  • Maria J. Lorenzo
  • Ulrich Preuss
  • Stephen J Ralston**
  • ADORE Study Group*
Article

Abstract

Objective

To describe the associations between a range of baseline factors (demographic, family and clinical) and parent-reported health-related quality of life (HRQoL) of children with ADHD taking part in the ADORE study.

Methods

HRQoL was rated using the Parent Report Form of the Child Health and Illness Profile-Child Edition (CHIP-CE). Forward-stepwise linear regression models were used to investigate associations with 26 independent variables. Separate models were fitted for each of the five CHIP-CE domains (Satisfaction, Comfort, Resilience, Risk Avoidance and Achievement) and two subdomains of Achievement (Academic Performance and Peer Relations).

Results

CHIP-CE domain mean scores were lower than community norms, especially for Risk Avoidance and Achievement, indicating a low level of HRQoL. Clinical factors significantly associated with a poorer HRQoL included ADHD symptoms (inattention, hyperactivity-impulsivity), conduct problems, peer relationship problems, having asthma, multiple other somatic symptoms and co-ordination problems. Family factors, such as having a parent with a health or mental health problem possibly caused by the child's illness, child not living with both parents and maternal smoking during pregnancy were also associated with a worse HRQoL in some CHIP-CE domains/subdomains.

Conclusions

Numerous factors independently impact on the HRQoL of children with ADHD.

Key words

ADHD children Europe health-related quality life 

Abbreviations

ADHD

Attention-Deficit/Hyperactivity Disorder

ADORE

Attention-deficit/hyperactivity Disorder Observational Research in Europe

ADHD-RS

ADHD Rating Scale

CD

Conduct Disorder

CGAS

Children's Global Assessment Scale

CGI-S

Clinical Global Impression-Severity scale

CHIP-CE

Child Health and Illness Profile – Child Edition

HRQoL

Health-Related Quality of Life

ODD

Oppositional Defiant Disorder

PRF

Parent Report Form

SDQ

Strengths and Difficulties Questionnaire

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Copyright information

© Steinkopff Verlag 2006

Authors and Affiliations

  • Anne W. Riley
    • 1
  • Georg Spiel
    • 2
  • David Coghill
    • 3
  • Manfred Döpfner
    • 4
  • Bruno Falissard
    • 5
  • Maria J. Lorenzo
    • 6
  • Ulrich Preuss
    • 7
  • Stephen J Ralston**
  • ADORE Study Group*
  1. 1.Johns Hopkins Bloomberg School of Public Health, 692 Hampton HouseBaltimore, MD 21205USA
  2. 2.Landeskrankenhaus Klagenfurt, Dept. of Child and Adolescent NeuropsychiatryKlagenfurtAustria
  3. 3.Section of Psychiatry, Division of Pathology and NeuroscienceUniversity of DundeeDundee, ScotlandUK
  4. 4.Dept. of Child and Adolescent PsychiatryUniversity of CologneCologneGermany
  5. 5.INSERM U669, Université Paris-SudParisFrance
  6. 6.Eli Lilly and Company, Lilly Research CentreWindlesham, SurreyUK
  7. 7.Dept. of Child and Adolescent PsychiatryUniversity of BernBernSwitzerland

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