European Child & Adolescent Psychiatry

, Volume 11, Issue 3, pp 138–141 | Cite as

A clinical case series of six extremely aggressive youths treated with olanzapine

  • Henrik Soderstrom
  • Maria Rastam
  • Christopher Gillberg
CASE REPORT

Abstract.

Olanzapine is an atypical neuroleptic drug with mood-stabilising properties and few of the side effects commonly associated with conventional neuroleptic treatment. We used olanzapine, 5-20 mg/day, to treat severe aggression in six non-psychotic teenage boys with neuropsychiatric disorders. All but one started to respond within one week. The therapeutic effect in four of the patients clearly outweighed the side effects (weight gain and sedation). The subjects described a markedly increased sense of well being during the olanzapine treatment.

Key words Olanzapine – violence – aggression – neuropsychiatry – adolescents 

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Copyright information

© Steinkopff-Verlag 2002

Authors and Affiliations

  • Henrik Soderstrom
    • 1
  • Maria Rastam
    • 2
  • Christopher Gillberg
    • 2
  1. 1.Department of Forensic Psychiatry, Box 4024, 422 04 Hisings Backa, Sweden and Department of Clinical Neuroscience, Göteborg University, Sweden. henrik.soderstrom@rmv.seSweden
  2. 2.Department of Child and Adolescent Psychiatry, 41119 Göteborg, Kungsgatan 12, SwedenSweden

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