Advertisement

Effect of photobiomodulation therapies on the root resorption associated with orthodontic forces: a pilot study using micro computed tomography

  • Merve GoymenEmail author
  • Aysegul Gulec
Original Article
  • 38 Downloads

Abstract

Objectives

The aim of this study is to investigate the effect of photobiomodulation therapies on root resorption compared with the placebo group.

Materials and methods

Thirty patients who were admitted to the Gaziantep University Faculty of Dentistry Orthodontics Department for treatment, with an indication of upper right first premolar tooth extraction were included. Before the individuals’ orthodontic treatment, 0.022 slot MBT brackets and tubes were placed on the maxillary first premolar and molar. A 150-g buccal tipping force was applied to the first premolar. Cantilever spring with 0.017 × 0.025 Beta Titanium wire was used for force application. Individuals were then randomly divided into three groups. For the first group, laser application was performed with an 810-nm GaAlAs laser device at 0, 3, 7, 14, 21, and 28 days to 8 J/cm2. For the second group, an LED application according to the manufacturer’s instructions with an 850-nm wavelength and 20 mW/cm2 output power for 10 min per day during the experiment. For the third group, a placebo therapy was completed whereby a laser device that did not make active pulses was used. At the end of 4 weeks, the amount of root surface resorption was compared using micro-CT imaging after the extraction of the teeth.

Results

No significant difference was found between the groups in terms of regional and total crater volumes. It was observed that photobiomodulation therapies were not different from the control group in terms of forming root resorption.

Conclusions

It is seen that laser and LED photobiomodulation therapies used for accelerate orthodontic tooth movement do not differ from the control group in terms of forming root resorption.

Clinical relevance

According to the results of this pilot study on this subject, which needs to be clarified with new findings in the future, LED and laser applications may not increase the risk for root resorption.

Keywords

Photobiomodulation Laser LED Resorption Micro-CT 

Notes

Funding information

The work was supported by the Coordinatorship of Scientific Research Projects, University of Gaziantep.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from participants included in the study.

References

  1. 1.
    Yamasaki K, Shibata Y, Imai S, Tani Y, Shibasaki Y, Fukuhara T (1984) Clinical application of prostaglandin E1 (PGE1) upon orthodontic tooth movement. Am J Orthod Dentofac Orthoped 85(6):508–518CrossRefGoogle Scholar
  2. 2.
    Long H, Pyakurel U, Wang Y, Liao L, Zhou Y, Lai W (2012) Interventions for accelerating orthodontic tooth movement: a systematic review. Angle Orthod 83(1):164–171PubMedCrossRefGoogle Scholar
  3. 3.
    Genc G, Kocadereli I, Tasar F, Kilinc K, El S, Sarkarati B (2013) Effect of low-level laser therapy (LLLT) on orthodontic tooth movement. Lasers Med Sci 28(1):41–47PubMedCrossRefGoogle Scholar
  4. 4.
    Nimeri G, Kau CH, Corona R, Shelly J (2014) The effect of photobiomodulation on root resorption during orthodontic treatment. Clin Cosmet Invest Dent 6(1):1–8Google Scholar
  5. 5.
    Brezniak N, Wasserstein A (2002) Orthodontically induced inflammatory root resorption. Part I: the basic science aspects. Angle Orthod 72(2):175–179PubMedGoogle Scholar
  6. 6.
    Krishnan V (2005) Critical issues concerning root resorption: a contemporary review. World J Orthod 6(1):30–40PubMedGoogle Scholar
  7. 7.
    Chan E, Dalci O, Petocz P, Papadopoulou AK, Darendeliler MA (2018) (2018) physical properties of root cementum: part 26. Effects of micro-osteoperforations on orthodontic root resorption: a microcomputed tomography study. Am J Orthod Dentofac Orthoped 153(2):204–213CrossRefGoogle Scholar
  8. 8.
    Altan AB, Bicakci AA, Mutaf HI, Ozkut M, Inan VS (2015) The effects of low-level laser therapy on orthodontically induced root resorption. Lasers Med Sci 30(8):2067–2076PubMedCrossRefGoogle Scholar
  9. 9.
    Suzuki SS, Garcez AS, Suzuki H, Ervolino E, Moon W, Ribeiro MS (2016) Low-level laser therapy stimulates bone metabolism and inhibits root resorption during tooth movement in a rodent model. J Biophotonics 9(11–12):1222–1235PubMedCrossRefGoogle Scholar
  10. 10.
    Vasconcelos EC, Henriques JFC, Sousa MVS, de Oliveira RC, Consolaro A, Pinzan A, Henriques FP, Bronfman CN (2016) Low-level laser action on orthodontically induced root resorption: histological and histomorphometric evaluation. J Lasers Med Sci 7(3):146–151PubMedPubMedCentralCrossRefGoogle Scholar
  11. 11.
    Yeh NG, Wu C-H, Cheng TC (2010) Light-emitting diodes—their potential in biomedical applications. Renew Sust Energ Rev 14(8):2161–2166CrossRefGoogle Scholar
  12. 12.
    Ekizer A, Uysal T, Guray E, Akkus D (2015) Effect of LED-mediated-photobiomodulation therapy on orthodontic tooth movement and root resorption in rats. Lasers Med Sci 30(2):779–785PubMedCrossRefGoogle Scholar
  13. 13.
    Fonseca P, Lima F, Higashi D, Koyama D, Filho OTD, Dias I, Ramos PS (2013) Effects of light emitting diode (LED) therapy at 940 nm on inflammatory root resorption in rats. Lasers Med Sci 28(1):49–55PubMedCrossRefGoogle Scholar
  14. 14.
    Higashi DT, Andrello AC, Tondelli PM, de Oliveira Toginho Filho D, de Paula RS (2017) Three consecutive days of application of LED therapy is necessary to inhibit experimentally induced root resorption in rats: a microtomographic study. Lasers Med Sci 32(1):181–187PubMedCrossRefGoogle Scholar
  15. 15.
    Huang TTY, Elekdag-Turk S, Dalci O, Almuzian M, Karadeniz EI, Gonzales C, Petocz P, Turk T, Darendeliler MA (2017) The extent of root resorption and tooth movement following the application of ascending and descending magnetic forces: a prospective split mouth, microcomputed-tomography study. Eur J Orthod 39(5):547–553PubMedCrossRefGoogle Scholar
  16. 16.
    Patterson BM, Dalci O, Papadopoulou AK, Madukuri S, Mahon J, Petocz P, Spahr A, Darendeliler MA (2017) Effect of piezocision on root resorption associated with orthodontic force: a microcomputed tomography study. Am J Orthod Dentofac Orthoped 151(1):53–62CrossRefGoogle Scholar
  17. 17.
    Malek S, Darendeliler MA, Swain MV (2001) Physical properties of root cementum: part I. A new method for 3-dimensional evaluation. Am J Orthod Dentofac Orthoped 120(2):198–208CrossRefGoogle Scholar
  18. 18.
    Malek S, Darendeliler MA, Rex T, Kharbanda OM, Srivicharnkul P, Swain MV, Petocz P (2003) Physical properties of root cementum: part 2. Effect of different storage methods. Am J Orthod Dentofac Orthoped 124(5):561–570CrossRefGoogle Scholar
  19. 19.
    Chan EKM, Darendeliler MA (2004) Exploring the third dimension in root resorption. Orthod Craniofac Res 7(2):64–70PubMedCrossRefGoogle Scholar
  20. 20.
    Ho C, Turk T, Elekdag-Turk S, Jones AS, Petocz P, Cheng LL, Darendeliler MA (2011) Physical properties of root cementum: part 19. Comparison of the amounts of root resorption between the right and left first premolars after application of buccally directed heavy orthodontic tipping forces. Am J Orthod Dentofac Orthoped 140(1):e49–e52CrossRefGoogle Scholar
  21. 21.
    AlSayed Hasan MMA, Sultan K, Hamadah O (2017) Evaluating low-level laser therapy effect on reducing orthodontic pain using two laser energy values: a split-mouth randomized placebo-controlled trial. Eur J Orthod 40(1):23–28CrossRefGoogle Scholar
  22. 22.
    Limpanichkul W, Godfrey K, Srisuk N, Rattanayatikul C (2006) Effects of low-level laser therapy on the rate of orthodontic tooth movement. Orthod Craniofac Res 9(1):38–43PubMedCrossRefGoogle Scholar
  23. 23.
    Luger EJ, Rochkind S, Wollman Y, Kogan G, Dekel S (1998) Effect of low-power laser irradiation on the mechanical properties of bone fracture healing in rats. Lasers Surg Med 22(2):97–102PubMedCrossRefGoogle Scholar
  24. 24.
    Ueda Y, Shimizu N (2001) Pulse irradiation of low-power laser stimulates bone nodule formation. J Oral Sci 43(1):55–60PubMedCrossRefGoogle Scholar
  25. 25.
    Karu TI, Pyatibrat LV, Kolyakov SF, Afanasyeva NI (2005) Absorption measurements of a cell monolayer relevant to phototherapy: reduction of cytochrome c oxidase under near IR radiation. J Photochem Photobiol B Biol 81(2):98–106CrossRefGoogle Scholar
  26. 26.
    Cheng LL, Turk T, Elekdag-Turk S, Jones AS, Petocz P, Darendeliler MA (2009) Physical properties of root cementum: part 13. Repair of root resorption 4 and 8 weeks after the application of continuous light and heavy forces for 4 weeks: a microcomputed-tomography study. Am J Orthod Dentofacial Orthop 136(3):320.e1–320.10Google Scholar
  27. 27.
    Chan E, Darendeliler MA (2005) Physical properties of root cementum: part 5. Volumetric analysis of root resorption craters after application of light and heavy orthodontic forces. Am J Orthod Dentofac Orthop 127(2):186–195CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Dentistry Faculty, Department of OrthodonticsGaziantep UniversityGaziantepTurkey

Personalised recommendations