Coexistence of oral lichen planus and pemphigus vulgaris
Letter to the Editor
- 117 Downloads
Over the past decades, several cases regarding the coexistence of two mucosal/skin-related autoimmune/inflammatory conditions have been reported. One of the least reported is the coexistence of pemphigus vulgaris (PV) and lichen planus (LP). Regardless of a few reports of coexistence of oral LP (OLP) or generalized LP with PV, which had been published more than two decades ago, none has been reported in the recent years [ 1, 2]. As a brief survey in registered cases of PV in Razi Hospital, Tehran University of Medical Sciences, we have focused on two patients affected with this coexistence. Both patients had a clinical and histopathological diagnosis of PV. Additionally, they had positive intercellular direct immunofluorescence and detectable autoantibodies against the desmoglein (Dsg)1 and/or Dsg3 at the beginning of their disease. Years after diagnosis of PV, OLP has been manifested in these patients. In contrast to their PV, which responded to conventional treatments,...
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- 4.Schmidt T, Solimani F, Pollmann R, Stein R, Schmidt A, Stulberg I, Kuhn K, Eming R, Eubel V, Kind P, Arweiler N, Sitaru C, Hertl M (2018) TH1/TH17 cell recognition of desmoglein 3 and bullous pemphigoid antigen 180 in patients with lichen planus. J Allergy Clin Immunol 142:669–672.e7. https://doi.org/10.1016/j.jaci.2018.02.044 CrossRefPubMedPubMedCentralGoogle Scholar
© Springer-Verlag GmbH Germany, part of Springer Nature 2018