Clinical Oral Investigations

, Volume 23, Issue 1, pp 87–98 | Cite as

Outcomes of autotransplanted teeth and prognostic factors: a 10-year retrospective study

  • Sujin Yang
  • Bock-Young Jung
  • Nan-Sim PangEmail author
Original Article



This retrospective study aimed to investigate the clinical outcome of tooth autotransplantation and related prognostic factors.

Materials and methods

Eighty-two cases of transplanted teeth from March 2006 to December 2016 were retrospectively investigated by medical records and radiographs. The clinical outcomes of transplanted teeth, which included tooth survival, inflammatory root resorption (IRR), ankylosis, and marginal bone loss (MBL), and the related prognostic factors were assessed via survival analysis.


The cumulative survival rate of transplanted teeth was 74% at 10 years after autotransplantation. According to Cox proportional hazards regression analysis, the eruption state of the donor tooth, recipient position, and postoperative MBL were significantly related to tooth survival. The donor tooth position was significantly associated with IRR, the recipient position and the timing of orthodontic initiation with ankylosis, and the recipient position with MBL.


Fully erupted donor teeth and a bounded recipient site were significantly associated with longer tooth survival. Periodontal healing and management to prevent postoperative MBL were as important for successful autotransplantation.

Clinical relevance

Knowledge about the prognostic factors that are significantly associated with each particular clinical outcome may guide clinicians to achieve predictable and successful outcomes after tooth transplantation.


Autotransplantation Survival analysis Postoperative complication Prognostic factor 



This study was supported by a faculty research grant from the Yonsei University College of Dentistry (No. 6-2014-0111).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors. The study was performed with the approval of the Institutional Review Board of Yonsei University Dental Hospital, Seoul, Korea (2-2017-0026). The study was performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Informed consent

For this type of study, formal consent is not required.


  1. 1.
    Nethander G (1995) Oral restoration with fixed partial dentures on transplanted abutment teeth. Int J Prosthodont 8:517–526Google Scholar
  2. 2.
    Kim E, Jung JY, Cha IH, Kum KY, Lee SJ (2005) Evaluation of the prognosis and causes of failure in 182 cases of autogenous tooth transplantation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100:112–119CrossRefGoogle Scholar
  3. 3.
    Thomas S, Turner S, Sandy J (1998) Autotransplantation of teeth: is there a role? Br J Orthod 25:275–282CrossRefGoogle Scholar
  4. 4.
    Mendes RA, Rocha G (2004) Mandibular third molar autotransplantation–literature review with clinical cases. J Can Dent Assoc 70:761–766Google Scholar
  5. 5.
    Kristerson L (1985) Autotransplantation of human premolars: a clinical and radiographic study of 100 teeth. Int J Oral Surg 14:200–213CrossRefGoogle Scholar
  6. 6.
    Almpani K, Papageorgiou SN, Papadopoulos MA (2015) Autotransplantation of teeth in humans: a systematic review and meta-analysis. Clin Oral Investig 19:1157–1179CrossRefGoogle Scholar
  7. 7.
    Jonsson T, Sigurdsson TJ (2004) Autotransplantation of premolars to premolar sites. A long-term follow-up study of 40 consecutive patients. Am J Orthod Dentofac Orthop 125:668–675CrossRefGoogle Scholar
  8. 8.
    Kvint S, Lindsten R, Magnusson A, Nilsson P, Bjerklin K (2010) Autotransplantation of teeth in 215 patients: a follow-up study. Angle Orthod 80:446–451CrossRefGoogle Scholar
  9. 9.
    Sugai T, Yoshizawa M, Kobayashi T, Ono K, Takagi R, Kitamura N, Okiji T, Saito C (2010) Clinical study on prognostic factors for autotransplantation of teeth with complete root formation. Int J Oral Maxillofac Surg 39:1193–1203CrossRefGoogle Scholar
  10. 10.
    Aoyama S, Yoshizawa M, Niimi K, Sugai T, Kitamura N, Saito C (2012) Prognostic factors for autotransplantation of teeth with complete root formation. Oral Surg Oral Med Oral Pathol Oral Radiol 114:S216–S228CrossRefGoogle Scholar
  11. 11.
    Andreasen J, Paulsen H, Yu Z, Schwartz O (1990) A long-term study of 370 autotransplanted premolars. Part III. Periodontal healing subsequent to transplantation. Eur J Orthod 12:25–37CrossRefGoogle Scholar
  12. 12.
    Watanabe Y, Mohri T, Takeyama M, Yamaki M, Okiji T, Saito C, Saito I (2010) Long-term observation of autotransplanted teeth with complete root formation in orthodontic patients. Am J Orthod Dentofac Orthop 138:720–726CrossRefGoogle Scholar
  13. 13.
    Lee SJ, Jung IY, Lee CY, Choi SY, Kum KY (2001) Clinical application of computer-aided rapid prototyping for tooth transplantation. Dent Traumatol 17:114–119CrossRefGoogle Scholar
  14. 14.
    Suzaki Y, Matsumoto Y, Kanno Z, Soma K (2008) Preapplication of orthodontic forces to the donor teeth affects periodontal healing of transplanted teeth. Angle Orthod 78:495–501CrossRefGoogle Scholar
  15. 15.
    Lundberg T, Isaksson S (1996) A clinical follow-up study of 278 autotransplanted teeth. Br J Oral Maxillofac Surg 34:181–185CrossRefGoogle Scholar
  16. 16.
    Saklad M (1941) Grading of patients for surgical procedures. Anesthesiology 2:281–284CrossRefGoogle Scholar
  17. 17.
    American Society of Anesthesiologists (2014) ASA physical status classification system. Accessed 21 September 2016
  18. 18.
    Andreasen J, Paulsen H, Yu Z, Bayer T (1990) A long-term study of 370 autotransplanted premolars. Part IV. Root development subsequent to transplantation. Eur J Orthod 12:38–50CrossRefGoogle Scholar
  19. 19.
    Tsukiboshi M (2002) Autotransplantation of teeth: requirements for predictable success. Dent Traumatol 18:157–180CrossRefGoogle Scholar
  20. 20.
    Fujita K, Kanno Z, Otsubo K, Soma K (2008) Autotransplantation combined with orthodontic treatment in adult patients. Orthodontic Waves 67:128–134CrossRefGoogle Scholar
  21. 21.
    Czochrowska EM, Stenvik A, Bjercke B, Zachrisson BU (2002) Outcome of tooth transplantation: survival and success rates 17-41 years posttreatment. Am J Orthod Dentofac Orthop 121:110–119CrossRefGoogle Scholar
  22. 22.
    Kallu R, Vinckier F, Politis C, Mwalili S, Willems G (2005) Tooth transplantations: a descriptive retrospective study. Int J Oral Maxillofac Surg 34:745–755CrossRefGoogle Scholar
  23. 23.
    Andreasen JO, Hjørting-Hansen E (1966) Replantation of teeth. I. Radiographic and clinical study of 110 human teeth replanted after accidental loss. Acta Odontol Scand 24:263–286CrossRefGoogle Scholar
  24. 24.
    Andreasen JO, Hjørting-Hansen E (1966) Replantation of teeth. II. Histological study of 22 replanted anterior teeth in humans. Acta Odontol Scand 24:287–306CrossRefGoogle Scholar
  25. 25.
    Andreasen JO, Andreasen FM, Andersson L (2007) Textbook and color atlas of traumatic injuries to the teeth. Blackwell, CopenhagenGoogle Scholar
  26. 26.
    Chung WC, Tu YK, Lin YH, Lu HK (2014) Outcomes of autotransplanted teeth with complete root formation: a systematic review and meta-analysis. J Clin Periodontol 41:412–423CrossRefGoogle Scholar
  27. 27.
    Jang Y, Choi YJ, Lee S-J, Roh B-D, Park SH, Kim E (2016) Prognostic factors for clinical outcomes in autotransplantation of teeth with complete root formation: survival analysis for up to 12 years. J Endod 42:198–205CrossRefGoogle Scholar
  28. 28.
    Kokai S, Kanno Z, Koike S, Uesugi S, Takahashi Y, Ono T, Soma K (2015) Retrospective study of 100 autotransplanted teeth with complete root formation and subsequent orthodontic treatment. Am J Orthod Dentofac Orthop 148:982–989CrossRefGoogle Scholar
  29. 29.
    Andreasen J, Paulsen H, Yu Z, Schwartz O (1990) A long-term study of 370 autotransplanted premolars. Part II. Tooth survival and pulp healing subsequent to transplantation. Eur J Orthod 12:14–24CrossRefGoogle Scholar
  30. 30.
    Hupp J, Mesaros S, Aukhil I, Trope M (1998) Periodontal ligament vitality and histologic healing of teeth stored for extended periods before transplantation. Dent Traumatol 14:79–83CrossRefGoogle Scholar
  31. 31.
    Kaneko S, Ohashi K, Soma K, Yanagishita M (2001) Occlusal hypofunction causes changes of proteoglycan content in the rat periodontal ligament. J Periodontal Res 36:9–17CrossRefGoogle Scholar
  32. 32.
    Shimomoto Y, Chung C, Iwasaki-Hayashi Y, Muramoto T, Soma K (2007) Effects of occlusal stimuli on alveolar/jaw bone formation. J Den Res 86:47–51CrossRefGoogle Scholar
  33. 33.
    Watarai H, Warita H, Soma K (2004) Effect of nitric oxide on the recovery of the hypofunctional periodontal ligament. J Den Res 83:338–342CrossRefGoogle Scholar
  34. 34.
    Turkyilmaz I, Tözüm T, Tumer C (2007) Bone density assessments of oral implant sites using computerized tomography. J Oral Rehabil 34:267–272CrossRefGoogle Scholar
  35. 35.
    Kon S, Novaes AB, Ruben M, Goldman H (1969) Visualization of microvascularization of the healing periodontal wound II. Curettage. J Periodontol 40:96–105CrossRefGoogle Scholar
  36. 36.
    Waerhaug J (1978) Healing of the dento-epithelial junction following subgingival plaque control: II: as observed on extracted teeth. J Periodontol 49:119–134CrossRefGoogle Scholar
  37. 37.
    Ahn JJ, Shin HI (2008) Bone tissue formation in extraction sockets from sites with advanced periodontal disease: a histomorphometric study in humans. Int J Oral Maxillofac Implants 23:1133–1138Google Scholar
  38. 38.
    Barone A, Aldini NN, Fini M, Giardino R, Calvo Guirado JL, Covani U (2008) Xenograft versus extraction alone for ridge preservation after tooth removal: a clinical and histomorphometric study. J Periodontol 79:1370–1377CrossRefGoogle Scholar
  39. 39.
    Van der Weijden F, Dell'Acqua F, Slot DE (2009) Alveolar bone dimensional changes of post-extraction sockets in humans: a systematic review. J Clin Periodontol 36:1048–1058CrossRefGoogle Scholar
  40. 40.
    Lindhe J, Svanberg G (1974) Influence of trauma from occlusion on progression of experimental periodontitis in the beagle dog. J Clin Periodontol 1:3–14CrossRefGoogle Scholar
  41. 41.
    Kessler M (1976) Interrelationships between orthodontics and periodontics. Am J Orthod 70:154–172CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Advanced General Dentistry, College of DentistryYonsei UniversitySeoulSouth Korea

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