How frequent does peri-implantitis occur? A systematic review and meta-analysis
- 1.4k Downloads
The objective of this study is to estimate the overall prevalence of peri-implantitis (PI) and the effect of different study designs, function times, and implant surfaces on prevalence rate reported by the studies adhering to the case definition of Sanz & Chapple 2012.
Material and methods
Following electronic and manual searches of the literature published up to February 2016, data were extracted from the studies fitting the study criteria. Meta-analysis was performed for estimation of overall prevalence of PI while the effects of the study design, function time, and implant surface type on prevalence rate were investigated using meta-regression method.
Twenty-nine articles were included in this study. The prevalence rate in all subset meta-analyses was always higher at patient level when compared to the prevalence rate at the implant level. Prevalence of PI was 18.5% at the patient level and 12.8% at the implant level. Meta-regression analysis did not identify any association for different study designs and function times while it was demonstrated the significant association between moderately rough surfaces with lower prevalence rate of PI (p = 0.011).
The prevalence rate of PI remains highly variable even following restriction to the clinical case definition and it seems to be affected by local factors such as implant surface characteristics. The identification of adjuvant diagnostic markers seems necessary for more accurate disease classification.
The occurrence of PI is affected by local factors such as implant surface characteristics hence the careful assessment of the local factors should be performed within treatment planning.
KeywordsPeri-implantitis Prevalence Dental implants Epidemiology
This study was supported by the Ministry of Education and Science, Republic of Serbia in Belgrade, Serbia (project references: no. 41008 and no. 173056).
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
For this type of study, formal consent is not required.
- 8.Schwarz F, Becker K, Sager M (2015) Efficacy of professionally administered plaque removal with or without adjunctive measures for the treatment of peri-implant mucositis. A systematic review and meta-analysis. J Clin Periodontol 42(Suppl 16):S202–S213. https://doi.org/10.1111/jcpe.12349 CrossRefPubMedGoogle Scholar
- 12.Tomasi C, Derks J (2012) Clinical research of peri-implant diseases—quality of reporting, case definitions and methods to study incidence, prevalence and risk factors of peri-implant diseases. J Clin Periodontol 39(s12):207–223. https://doi.org/10.1111/j.1600-051X.2011.01831.x CrossRefPubMedGoogle Scholar
- 18.Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med 151(4):W65–W94CrossRefPubMedGoogle Scholar
- 19.Zeng X, Zhang Y, Kwong JS et al (2015) The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review. J Evid Based Med 8(1):2–10. https://doi.org/10.1111/jebm.12141 CrossRefPubMedGoogle Scholar
- 21.Khan KS, ter Riet G, Glanville J, Sowden AJ, Kleijnen J (2001) Undertaking systematic reviews of research on Efectiveness, ed 2 edn. University of York, York, pp 1–20Google Scholar
- 28.Becker ST, Beck-Broichsitter BE, Rossmann CM, Behrens E, Jochens A, Wiltfang J (2015) Long-term survival of Straumann dental implants with TPS surfaces: a retrospective study with a follow-up of 12 to 23 years. Clin Implant Dent Relat Res 18(3):480–488. https://doi.org/10.1111/cid.12334 CrossRefPubMedGoogle Scholar
- 29.Buser D, Janner SF, Wittneben JG, Bragger U, Ramseier CA, Salvi GE (2012) 10-year survival and success rates of 511 titanium implants with a sandblasted and acid-etched surface: a retrospective study in 303 partially edentulous patients. Clin Implant Dent Relat Res 14(6):839–851. https://doi.org/10.1111/j.1708-8208.2012.00456.x CrossRefPubMedGoogle Scholar
- 34.Dierens M, Vandeweghe S, Kisch J, Nilner K, De Bruyn H (2012) Long-term follow-up of turned single implants placed in periodontally healthy patients after 16-22 years: radiographic and peri-implant outcome. Clin Oral Implants Res 23(2):197–204. https://doi.org/10.1111/j.1600-0501.2011.02212.x CrossRefPubMedGoogle Scholar
- 39.Jemt T, Sunden Pikner S, Grondahl K (2015) Changes of marginal bone level in patients with “progressive bone loss” at Branemark system(R) implants: a radiographic follow-up study over an average of 9 years. Clin Implant Dent Relat Res 17(4):619–628. https://doi.org/10.1111/cid.12166 CrossRefPubMedGoogle Scholar
- 43.Maximo MB, de Mendonca AC, Alves JF, Cortelli SC, Peruzzo DC, Duarte PM (2008) Peri-implant diseases may be associated with increased time loading and generalized periodontal bone loss: preliminary results. J Oral Implantol 34(5):268–273. https://doi.org/10.1563/1548-1336(2008)34[269:PDMBAW]2.0.CO;2 CrossRefPubMedGoogle Scholar
- 49.Rodrigo D, Martin C, Sanz M (2012) Biological complications and peri-implant clinical and radiographic changes at immediately placed dental implants. A prospective 5-year cohort study. Clin Oral Implants Res 23(10):1224–1231. https://doi.org/10.1111/j.1600-0501.2011.02294.x CrossRefPubMedGoogle Scholar
- 51.Rutar A, Lang NP, Buser D, Burgin W, Mombelli A (2001) Retrospective assessment of clinical and microbiological factors affecting periimplant tissue conditions. Clin Oral Implants Res 12(3):189–195. https://doi.org/10.1034/j.1600-0501.2001.012003189.x CrossRefPubMedGoogle Scholar
- 53.van Velzen FJ, Ofec R, Schulten EA, Ten Bruggenkate CM (2015) 10-year survival rate and the incidence of peri-implant disease of 374 titanium dental implants with a SLA surface: a prospective cohort study in 177 fully and partially edentulous patients. Clin Oral Implants Res 26(10):1121–1128. https://doi.org/10.1111/clr.12499 CrossRefPubMedGoogle Scholar
- 55.Zetterqvist L, Feldman S, Rotter B, Vincenzi G, Wennström JL, Chierico A, Stach RM, Kenealy JN (2010) A prospective, multicenter, randomized-controlled 5-year study of hybrid and fully etched implants for the incidence of peri-implantitis. J Periodontol 81(4):493–501. https://doi.org/10.1902/jop.2009.090492 CrossRefPubMedGoogle Scholar
- 60.Esposito M, Ardebili Y, Worthington HV (2014) Interventions for replacing missing teeth: different types of dental implants. Cochrane Database Syst Rev (7):CD003815. https://doi.org/10.1002/14651858.CD003815.pub4
- 64.Bragger U, Aeschlimann S, Bürgin W, Hämmerle CHF, Lang NP (2001) Biological and technical complications and failures with fixed partial dentures (FPD) on implants and teeth after four to five years of function. Clin Oral Implants Res 12(1):26–34. https://doi.org/10.1034/j.1600-0501.2001.012001026.x CrossRefPubMedGoogle Scholar
- 65.Bragger U, Karoussis I, Persson R, Pjetursson B, Salvi G, Lang N (2005) Technical and biological complications/failures with single crowns and fixed partial dentures on implants: a 10-year prospective cohort study. Clin Oral Implants Res 16(3):326–334. https://doi.org/10.1111/j.1600-0501.2005.01105.x CrossRefPubMedGoogle Scholar
- 66.Ladeira Casado P, Villas-Boas R, de Mello W, Leite Duarte ME, Mauro GJ (2013) Peri-implant disease and chronic periodontitis: is interleukin-6 gene promoter polymorphism the common risk factor in a Brazilian population. Int J Oral Maxillofac Implants 28(1):35–43. 10.11607/jomi.2867 CrossRefGoogle Scholar
- 68.Schmidlin K, Schnell N, Steiner S, Salvi GE, Pjetursson B, Matuliene G, Zwahlen M, Bragger U, Lang NP (2010) Complication and failure rates in patients treated for chronic periodontitis and restored with single crowns on teeth and/or implants. Clin Oral Implants Res 21(5):550–557. https://doi.org/10.1111/j.1600-0501.2009.01907.x CrossRefPubMedGoogle Scholar