Clinical Oral Investigations

, Volume 21, Issue 2, pp 567–571 | Cite as

Effect of root canal irrigating solutions on the compressive strength of tricalcium silicate cements

  • Lokhasudhan Govindaraju
  • Prasanna Neelakantan
  • James L. Gutmann
Original Article



The aim of this study was to evaluate the effect of root canal irrigants on the compressive strength of hydraulic tricalcium silicate cements.

Materials and methods

Specimens (n = 60) of tricalcium silicate materials—Group 1: White ProRoot mineral trioxide aggregate (MTA), Group 2: NeoMTA Plus, Group 3: White MTA Angelus, and Group 4: Biodentine were exposed to one of the solutions (n = 20): Phosphate buffered saline (PBS; control), 3 % NaOCl, or 17 % EDTA for 5 min while being suspended in PBS. Compressive strength values were evaluated after 7 days of storage. The data were statistically analyzed by two-way ANOVA and Tukey’s multiple comparison test (P = 0.05).


Biodentine (BD) showed significantly higher compressive strength than the other materials (P < 0.05) in the control group. When exposed to NaOCl, compressive strength of WMTA and WMTA-A decreased significantly (P < 0.05), while EDTA decreased the compressive strength of all the cements compared to the control (P < 0.05). There was no significant difference in the compressive strength of BD and NMTA-P when exposed to NaOCl or EDTA.


Biodentine and NeoMTA Plus did not show a significant reduction in compressive strength when exposed to NaOCl. EDTA reduced the compressive strength of the cements tested.

Clinical significance

Tricalcium silicates were differentially influenced by root canal irrigants. It is essential to understand the composition of these materials prior to clinical use. Traces of irrigants from the root canal wall must be thoroughly removed.


Bismuth oxide EDTA Mineral trioxide aggregate Sodium hypochlorite Tantalite Zirconium oxide 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


The work was self-funded.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

For this type of study, formal consent is not required.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Lokhasudhan Govindaraju
    • 1
  • Prasanna Neelakantan
    • 2
  • James L. Gutmann
    • 3
  1. 1.Department of Conservative Dentistry and Endodontics, Saveetha Dental College and HospitalsSaveetha UniversityChennaiIndia
  2. 2.Department of Conservative Dentistry and Endodontics, Saveetha Dental College and HospitalsSaveetha UniversityChennaiIndia
  3. 3.Texas A&M University Baylor College of DentistryDallasUSA

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