Clinical Oral Investigations

, Volume 21, Issue 4, pp 1277–1282 | Cite as

Effect of double antibiotic and calcium hydroxide pastes on dislodgement resistance of an epoxy resin-based and two calcium silicate-based root canal sealers

  • Hakan Gokturk
  • Emre Bayram
  • Huda Melike Bayram
  • Tugrul Aslan
  • Yakup Ustun
Original Article



The purpose of the present study was to determine the dislodgement resistance of AH Plus, MTA Fillapex, and Total Fill BC sealer to root canal dentin walls following placement of calcium hydroxide (CH) or double antibiotic paste (DAP) medicaments.

Materials and methods

Root canals of 90 single-rooted human mandibular premolar teeth were instrumented with Reciproc rotary instruments to a size R50. The teeth were randomly divided into two experimental groups: those receiving an intracanal medicament with either CH or DAP and a control group (n = 30). After 3 weeks, the medicaments were removed by irrigation with 5 mL of 2.5 % NaOCl, 5 mL 17 % EDTA, and 5 mL distilled water under sonic agitation. Each group was then subdivided into three subgroups (n = 10), and the canals were filled with either AH Plus, MTA Fillapex, or Total Fill BC sealer. After 1 week, a push-out test was applied to the specimens and the results were analyzed using one-way analysis of variance (ANOVA) and post hoc Tamhane’s tests.


Regardless of the type of intracanal medicament used, Total Fill BC Sealer and MTA Fillapex showed the highest and lowest bond strength, respectively (P < 0.05). The use or absence of medicaments did not significantly affect the dislodgment resistance of root canal fillings (P > 0.05). Prior CH placement improved dislodgement resistance of all sealers without statistical difference (P > 0.05). Adhesive failure between core and sealer was the most frequent failure mode.


Prior application of CH or DAP did not significantly affect the adhesion of the AH Plus, MTA Fillapex, and Total Fill BC Sealers.

Clinical relevance

There is a little information about the influence of antibiotic medicaments on the bond strength of root canal sealer. These findings suggest that the use of DAP does not affect the adhesion strength of AH Plus, MTA Fillapex, and Total Fill BC Sealers.


Bond strength Calcium hydroxide Double antibiotic paste Resin-based sealer Calcium silicate-based sealer 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.



Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Hakan Gokturk
    • 1
  • Emre Bayram
    • 1
  • Huda Melike Bayram
    • 1
  • Tugrul Aslan
    • 2
  • Yakup Ustun
    • 2
  1. 1.Department of Endodontics, Faculty of DentistryGaziosmanpaşa UniversityTokatTurkey
  2. 2.Department of Restorative Dentistry and Endodontics, Faculty of DentistryErciyes UniversityKayseriTurkey

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