Clinical Oral Investigations

, Volume 19, Issue 6, pp 1299–1305 | Cite as

The relationship between resting arterial blood pressure and oral postsurgical pain

  • Christophe Deschaumes
  • Laurent Devoize
  • Yannick Sudrat
  • Martine Baudet-Pommel
  • Christian Dualé
  • Radhouane Dallel
Original Article



This prospective study examined the relationship between resting blood pressure (BP; primary outcome), demographic features of patients, anatomical characteristics of the extracted teeth, surgery variables (secondary outcomes), and acute postsurgical pain in patients undergoing tooth extraction.

Materials and methods

Standardized surgery was performed under local anesthesia. A composite numerical index, referred to as “postoperative pain/analgesia score” (PPAS), was built out of two intermediate ones, indicating (i) the degree of spontaneous pain reported by the patient (postoperative pain score) and (ii) the amount of analgesic drug intake (postoperative analgesia score).


A total of 293 patients with complete data sets were included in the analysis. Univariate analysis reveals that the intensity of postoperative pain is related to age, history of hypertension and previous oral surgery, number of extracted teeth, duration of surgery, and extraction of the third molar. On the other hand, there is no relationship with gender, anxiety, and operation duration. Multivariate analysis reveals that the intensity of acute postoperative pain is only associated with the location (upper/lower jaw, P = 0.004) and deepness of implantation of the extracted tooth (P < 0.0001), and mean resting BP (P = 0.031).


This large prospective study shows that patients with high resting BP had a lower oral postsurgical pain than those with low resting BP. This suggests that high resting BP is a protective factor against oral postsurgical pain.

Clinical relevance

The measurement of resting BP before surgery may be used in clinical practice to identify patients at risk of developing severe oral postsurgical pain.


Blood pressure Tooth extraction Hypertension Hypoalgesia Prediction 



We thank Pr A Artola for helpful comments on this manuscript and A-M Gaydier for secretarial assistance.


This work was supported by funding from Institut National de la Santé et de la Recherche Médicale (INSERM), Université Clermont1 (France), and CHU Clermont-Ferrand (France).

Conflict of interest

The authors declare to have no conflict of interest related to this study.

Supplementary material

784_2014_1356_MOESM1_ESM.doc (70 kb)
ESM 1 (DOC 70 kb)


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Christophe Deschaumes
    • 1
    • 2
  • Laurent Devoize
    • 1
    • 2
  • Yannick Sudrat
    • 1
    • 2
  • Martine Baudet-Pommel
    • 1
    • 2
  • Christian Dualé
    • 1
    • 3
  • Radhouane Dallel
    • 1
    • 2
    • 4
  1. 1.Clermont Université, Université d’Auvergne, Neuro-DolClermont-Ferrand and InsermFrance
  2. 2.CHU Clermont-Ferrand, Service d’OdontologieClermont-FerrandFrance
  3. 3.CHU Clermont-Ferrand, Inserm, CIC 50Clermont-FerrandFrance
  4. 4.INSERM/UdA U1107, Neuro-Dol: Douleur Trigéminale et Migraine, Faculté de Chirurgie Dentaire63100 Clermont-FerrandFrance

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