Abstract
Objectives
Mandibular distraction osteogenesis (MDO) has been successfully applied in infants suffering Robin sequence (RS) with severe upper airway obstruction, but no comparative studies for the different types of MDO exist to date. The objective of the current study was to systematically review the published data considering this matter, providing a fundament for protocols and a more conscious treatment strategy for infants with RS in the near future.
Material and methods
For the period from January 1966 to January 2012, the Pubmed, EMBASE, and Cochrane Library databases were searched. Abstracts were screened based on predetermined selection criteria. Relevant full-text articles were retrieved. The articles were analyzed on the type of MDO used, preoperative workup, patient characteristics, postoperative outcome, and complications.
Results
The search yielded 109 articles. After checking abstracts and full texts on predetermined inclusion and exclusion criteria, 12 studies (four describing external MDO, five internal MDO, and three both types) were extracted for further analyses.
Conclusion
Internal MDO seems very feasible in infants suffering RS, minimizing side effects such as hypertrophic scarring, nerve damage, and extensive care needs, although the indications for usage are more limited compared to the external device. Corresponding protocols and long-term outcome studies are needed to make a better comparison and the use and indication of the different types of distraction even more distinct.
Clinical relevance
A base for a guideline to support the choice of a designated operative management for neonates with RS is provided, hereby obviating possible complications of the different types of MDO in the future.
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The authors declare that they have no conflict of interest.
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This work has been presented at the biannual meeting of the Dutch Society of Plastic and Reconstructive Surgery, 8 October 2011.
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Paes, E.C., Mink van der Molen, A.B., Muradin, M.S.M. et al. A systematic review on the outcome of mandibular distraction osteogenesis in infants suffering Robin sequence. Clin Oral Invest 17, 1807–1820 (2013). https://doi.org/10.1007/s00784-013-0998-z
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DOI: https://doi.org/10.1007/s00784-013-0998-z