Clinical Oral Investigations

, Volume 16, Issue 5, pp 1395–1399 | Cite as

Caries-preventive and remineralizing effect of fluoride gel in orthodontic patients after 2 years

  • Christian H. SpliethEmail author
  • Anja Treuner
  • Tomasz Gedrange
  • Christine Berndt
Original Article


Patients with orthodontic appliances exhibit a higher caries risk, but they are often excluded from preventive studies. Thus, the aim of this observational study was to assess the caries-preventive and remineralizing effect of a high-fluoride gel in orthodontic patients. Two hundred twenty-one orthodontic patients (age, 6–19 years; mean, 13.1 ± 2.3; n = 104 with use of a 1.25% fluoride gel weekly at home, 117 participants without) were recruited and followed for 2 years, recording caries (decayed/missing/filled teeth (DMFT)/decayed/missing/filled surface (DMFS), active/inactive lesions), orthodontic treatment, use of fluorides, plaque and gingivitis. Baseline values regarding demographic and clinical parameters were equivalent for the 75 participants using fluoride gel and the 77 individuals of the control group who completed the study. The initial plaque and gingivitis values (approximal plaque index (API), 37% ± 34 and 42% ± 39, resp.; papillary bleeding index (PBI), 19% ± 28 and 22% ± 27, resp.) deteriorated slightly during the 2-year study (API, 54%/56%; PBI, 25%/28%). The increase in carious defects or fillings was minimal in both groups (fluoride, 0.75 DMFT ± 1.2, 1.27 DMFS ± 1.9; control, 0.99 ± 1.3 and 1.62 ± 2.6, resp.) without reaching statistical significance (p = 0.12 for DMFT, 0.44 for DMFS). The main statistically significant effect of the fluoride use was the reversal of active initial lesions diagnosed (fluoride group, −0.96 ± 1.82; control, −0.19 ± 2.0, p = 0.004), while the number of inactive initial lesions increased (2.3 ± 2.1 and 1.7 ± 2.1, resp.; p = 0.02). In conclusion, the weekly application of a fluoride gel in orthodontic patients can reduce their caries activity. Initial caries lesions in orthodontic patients can be inactivated by weekly fluoride gel use at home.


Fluoride High caries risk Initial lesions Prevention Orthodontics 



The authors would like to thank Dr. A. Riedel and Dr. Dr. T. Gredes for their support to recruit orthodontic patients. This study was supported by GABA International.

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Christian H. Splieth
    • 1
    Email author
  • Anja Treuner
    • 1
  • Tomasz Gedrange
    • 1
  • Christine Berndt
    • 1
  1. 1.Department of Orthodontics, Preventive and Pediatric Dentistry, Center for Oral HealthErnst Moritz Arndt University GreifswaldGreifswaldGermany

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