Clinical Oral Investigations

, Volume 15, Issue 2, pp 127–139

Oral chronic graft-versus-host disease: report from the International Consensus Conference on clinical practice in cGVHD

  • Johannes K.-H. Meier
  • Daniel Wolff
  • Steve Pavletic
  • Hildegard Greinix
  • Martin Gosau
  • Hartmut Bertz
  • Stefanie J. Lee
  • Ánita Lawitschka
  • Sharon Elad
Review

Abstract

Chronic graft-versus-host disease (cGVHD) is a multi-organ disease that occurs post-hematopoietic stem cell transplantation, with the mouth being one of the most frequently affected organs. In 2009, the German–Austrian–Swiss working party on bone marrow and blood stem cell transplantation held a consensus conference to define clinical management of cGVHD. The consensus conference aimed to summarize the literature on diagnosis and topical treatment options for oral cGVHD and to provide recommendations for clinical practice, including routine dental and oral care as well as monitoring for secondary malignancies and bisphophonate-induced osteonecrosis of the jaw.

Keywords

Oral cGVHD Topical Treatment Diagnosis 

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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Johannes K.-H. Meier
    • 1
  • Daniel Wolff
    • 2
  • Steve Pavletic
    • 3
  • Hildegard Greinix
    • 4
  • Martin Gosau
    • 1
  • Hartmut Bertz
    • 5
  • Stefanie J. Lee
    • 6
  • Ánita Lawitschka
    • 7
  • Sharon Elad
    • 8
  1. 1.Department of Cranio-Maxillo-Facial SurgeryUniversity of RegensburgRegensburgGermany
  2. 2.Department of Haematology and OncologyUniversity of RegensburgRegensburgGermany
  3. 3.Experimental Transplantation and Immunology Branch, Center of Cancer ResearchNational Cancer InstituteBethesdaUSA
  4. 4.Department of Internal Medicine IMedical University of ViennaViennaAustria
  5. 5.Department of Haematology and OncologyAlbert Ludwigs University Medical Centre FreiburgFreiburgGermany
  6. 6.Division of Clinical ResearchFred Hutchinson Cancer Research CenterSeattleUSA
  7. 7.Department of stem cell transplantationSt. Anna Children’s HospitalViennaAustria
  8. 8.Department of Oral MedicineThe Hebrew University—Hadassah School of Dental MedicineJerusalemIsrael

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