Clinical Oral Investigations

, Volume 14, Issue 3, pp 265–269 | Cite as

Remineralization of initial carious lesions in deciduous enamel after application of dentifrices of different fluoride concentrations

  • Elmar Hellwig
  • Markus Altenburger
  • Thomas Attin
  • Adrian Lussi
  • Wolfgang Buchalla
Original Article


The aim of the present study was to evaluate the remineralization potential of five dentifrices with different fluoride concentrations. Initial caries lesions were created in 72 cylindrical enamel blocks from deciduous teeth. The specimens were randomly distributed among six experimental groups corresponding to six experimental periods. Each of the six volunteers carried two deciduous enamel specimens fixed in an intraoral appliance for a period of 4 weeks. They brushed their teeth and the enamel blocks at least two times a day with dentifrices containing 0 ppm (period 1), 250 ppm (period 2), and 500 ppm fluoride (period 3), respectively. A second group of volunteers (n = 6) used dentifrices with a fluoride content of 0 ppm (period 4), 1,000 ppm (period 5), or 1,500 ppm (period 6). At the end of the respective period, the mineral content was determined by transversal microradiography (TMR). The use of dentifrices containing 500 ppm fluoride (38% MR), 1,000 ppm fluoride (42% MR), and 1,500 ppm fluoride (42% MR) resulted in a statistically significant higher mineral recovery compared to the control group (0 ppm fluoride). Mineral recovery was similar after use of dentifrices containing 0 and 250 ppm fluoride (24%; 25%). It is concluded that it is possible to remineralize initial carious lesions in deciduous enamel in a similar way as it has been described for enamel of permanent teeth.


Fluoride Dentifrices Carious lesions Remineralization Deciduous teeth 



We gratefully acknowledge the support of GABA International AG, Bale/Switzerland.

The authors thank Ms. Petra Heß for her excellent assistance.

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Elmar Hellwig
    • 1
  • Markus Altenburger
    • 1
  • Thomas Attin
    • 2
  • Adrian Lussi
    • 3
  • Wolfgang Buchalla
    • 2
  1. 1.Department of Operative Dentistry and Periodontology, Dental School and HospitalAlbert-Ludwigs-University FreiburgFreiburgGermany
  2. 2.Department of Preventive Dentistry, Periodontology and Cariology, Center for Dental and Oral Medicine and Cranio-Maxillofacial SurgeryUniversity of ZurichZürichSwitzerland
  3. 3.Department of Preventive, Restorative and Pediatric Dentistry, School of Dental MedicineUniversity of BernBern 10Switzerland

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