JBIC Journal of Biological Inorganic Chemistry

, Volume 16, Issue 8, pp 1135–1140 | Cite as

Biocompatible hydroxyapatite nanoparticles as a redox luminescence switch

Report
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Abstract

A redox luminescence switch was prepared by doping hydroxyapatite nanoparticles with CePO4:Tb. The resulting multifunctional material exhibits good biocompatibility, biological affinity, and potential drug-carrying capability. The luminescent hydroxyapatite nanoparticles may find important applications in biomedical diagnostics, drug delivery, and biological sensors.

Graphical abstract

This work demonstrated a biocompatible redox luminescence switch based on hydroxyapatite nanoparticles. The as-synthesized multifunctional nanoparticles have a large surface area and exhibit high biological affinity. This study will be quite relevant for developing a new system that may be applied in studying enzyme or protein activities based on fluorescent nanoparticles.

Keywords

Redox luminescence switch Hydroxyapatite Protein adsorption Biocompatibility 
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Notes

Acknowledgments

This study was supported by the Foundation of Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, State Key Laboratory of Applied Organic Chemistry, and the NSFC (20171019).

Supplementary material

775_2011_815_MOESM1_ESM.pdf (652 kb)
Supplementary material (PDF 651 kb)

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Copyright information

© SBIC 2011

Authors and Affiliations

  1. 1.Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhouPeople’s Republic of China
  2. 2.School of Basic Medical SciencesLanzhou UniversityLanzhouPeople’s Republic of China

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