Journal of Bone and Mineral Metabolism

, Volume 26, Issue 2, pp 199–202

Two patients with osteoporosis: initial presentation of systemic mastocytosis

  • Marjolein L. Donker
  • Nicolaas A. Bakker
  • Wim J. M. Jaspers
  • Albert H. Verhage
Case Report

DOI: 10.1007/s00774-007-0800-x

Cite this article as:
Donker, M.L., Bakker, N.A., Jaspers, W.J.M. et al. J Bone Miner Metab (2008) 26: 199. doi:10.1007/s00774-007-0800-x

Abstract

In two patients with osteoporosis, systemic mastocytosis ultimately turned out to be the underlying disease. Both patients had a history of anaphylactic reactions caused by wasp stings but did not have any skin or other symptoms. This observation reflects the need for careful history taking and physical examination in patients with osteoporosis to identify possible underlying diseases, such as systemic mastocytosis.

Key words

osteoporosis systemic mastocytosis tryptase 

Copyright information

© Springer Japan 2008

Authors and Affiliations

  • Marjolein L. Donker
    • 1
  • Nicolaas A. Bakker
    • 1
  • Wim J. M. Jaspers
    • 2
  • Albert H. Verhage
    • 2
  1. 1.Department of Hematology, University Medical Center GroningenUniversity of GroningenGroningenthe Netherlands
  2. 2.Department of Internal MedicineSt. Lucas HospitalWinschotenthe Netherlands

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