Journal of Bone and Mineral Metabolism

, Volume 24, Issue 5, pp 419–424 | Cite as

Clinical factors as predictors of the risk of falls and subsequent bone fractures due to osteoporosis in postmenopausal women

  • Taiki Komatsu
  • Kang Jung Kim
  • Tetsuo Kaminai
  • Hiroyasu Okuizumi
  • Hiroharu Kamioka
  • Shinpei Okada
  • Hyuntae Park
  • Ayumi Hasegawa
  • Yoshiteru Mutoh
  • Iwao Yamamoto


In Japan, the “bedridden state” is one of the most serious problems the aged face, and it is becoming a social problem. The main causes of the bedridden state are cerebrovascular disorders and bone fractures following falls. The purpose of this study was to predict risk factors for falls and resultant bone fracture due to osteoporosis. We explored mobility parameters for possible fall prevention. In order to examine the correlation between the risk of falling and resultant bone fracture due to osteoporosis, logistic regression analysis was performed between bone mass (independent variable) and various factors dependent variables: body mass index [BMI], body fat percentage, atherogenic index, presence of transformation-related osteoarthritis of knee, presence of transformation-related osteoarthritis of spine, maximum step length, single-leg stance with open eyes, and hip-joint flexion motion angle); predictive factors were then examined. Predictive factors were determined by the stepwise method. Subjects who could not perform the “single-leg stance with open eyes” test had a risk of falling and bone fracture 2.49 times as large as that of subjects who could. The “single-leg stance with open eyes” test may be considered a useful method for the early detection of the risk of falling and bone fracture associated with osteoporosis. As a first step to identify factors predicting the occurrence of falls and bone fractures due to osteoporosis, we intended to discover an indicator that would help to detect incipient osteoporosis.

Key words

osteoporosis falls single-leg stance with open eyes predictive factors logistic regression analysis 


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  1. 1.
    Annual report an health and welfare2000

    Old People and Health (in Japanese)

    Ministry of Health and WelfareGyoseiTokyo5885
    Google Scholar
  2. 2.
    Yanagisawa, N 2000

    Importance of Prevention of Bedridden Conditions in Ageing Societies

    Japan Foundation For Aging and Health (in Japanese)Hoken-dohjinshaTokyo916
    Google Scholar
  3. 3.
    Orimo, H, Hosoda, Y, Fujiwara, S, Mizuno, S, Hashimoto, T, Tamaki, T, Nose, T, Yamamoto, K, Sasaki, R 1991Hip fracture incidence in JapanJ Bone Miner Metab98993Google Scholar
  4. 4.
    Orimo, H, Hashimoto, T, Yoshimura, N, Fujiwara, S, Hosoi, T, Shiraki, M, Fukunaga, M, Nakamura, T, Fukushima, Y, Yamamoto, K 1996Nationwide incidence survey of femoral neck fracture in JapanJ Bone Miner Metab15100106Google Scholar
  5. 5.
    Orimo, H, Hashimoto, T, Sakata, K, Yoshimura, N, Seino, Y, Emi, M, Suzuki, T, Hosoi, T, Miyao, M 1999Third national frequency investigation results of femoral neck fracture. Estimation of new generated patient numbers in 1997 and transition for 10 years (in Japanese)Japan Medical Journal39164649Google Scholar
  6. 6.
    Province, MA Hardly, EC Hornbrook, MC Lipsitz, LA Miller, JP Mulrow, CD Ory, MG Sattin, RW Tinetti, ME Wolf SL for the FICSIT Group1995The effects of exercise on falls in elderly patients. A preplanned meta-analysis of FICSIT trialsJAMA27313711347CrossRefGoogle Scholar
  7. 7.
    Cummings, SR, Black, DM, Nevitt, MC, Browner, W, Cauley, J, Ensrud, K, Genant, HK, Palermo, L, Scott, J, Vogt, TM 1993Bone density at various sites for prediction of hip fracture. The Study of Osteoporotic Fracture Research GroupLancet3417275PubMedCrossRefGoogle Scholar
  8. 8.
    Dargent-Molina, P, Schott, AM, Hans, D, Favier, F, Grandjean, H, Baudoin, C, Meunier, PJ, Breart, G 1999Separate and combined value of bone mass and gait speed measurement in screening for hip fracture risk: results from the EPIDOS StudyOsteoporosis Int9188192CrossRefGoogle Scholar
  9. 9.
    Garnero, P, Hausherr, E, Chapuy, MC, Marcelli, C, Grandjean, H, Muller, C, Cormier, C, Breart, G, Meunier, PJ, Delmas, PD 1996Markers of bone resorption predict hip fracture in elderly women: the EPIDOS Prospective Study Bone Miner Res1115131425Google Scholar
  10. 10.
    The 2003 Cochrane Library, Issue 1Google Scholar
  11. 11.
    Shichita, K, Endo, C, Shibazaki, K, Karube, S, Oda, H, Igarashi, M, Hayashi, Y 1988Survival rate and physical activity in elderly patients after femoral neck fracture (in Japanese with English summary)Jpn J Geriatr25563568Google Scholar
  12. 12.
    Ohta, M, Mutoh, Y, Kuroyanagi, R, Ueno, K 1998Outline of “Fall Prevention School for the Elderly” in Tokyo Koseinekin Hospital (in Japanese)Osteoporosis Jpn6598600Google Scholar
  13. 13.
    Ohta, M, Mutoh, Y, Kamioka, H, Takasugi, S, Yasuda, K 1997Relation between actual conditions of falling in old people and physical characters (in Japanese)Japan Medical Journal38372632Google Scholar
  14. 14.
    Orimo, H, Hayashi, Y, Fukunaga, H, Fujiwara, S, Shiraki, M, Kushida, K, Sohen, S, Nishimura, J, Kishimoto, H 2001A diagnosis standard (2000 revised edition) of primary osteoporosis (in Japanese)Japan Society of Bone Metabolism187682Google Scholar
  15. 15.
    Aoyagi, K, Ross, PD, Davis, JW, Wanich, RD, Hayashi, T, Takemoto, T 1998Falls among community-dwelling elderly in JapanJ Bone Miner Res1314681474PubMedCrossRefGoogle Scholar
  16. 16.
    Ross, PD, Huang, C 1997Hip fracture incidence for both caucasians and Japanese in Hawaii is lower than in North AmericaJ Bone Miner Res12173SGoogle Scholar
  17. 17.
    Lipsitz, LA, Nakajima, I, Gagnon, M, Hirayama, T, Connelly, CM, Izumo, H, Hirayama, T 1994Muscle strength and fall rates among residents of Japanese and American nursing homes: an international cross-cultural studyJ Am Geriatr Soc42953959PubMedGoogle Scholar
  18. 18.
    Suzuki, T, Sugiura, M, Furuna, S, Nishizawa, T, Yoshida, H, Ishibashi, T, Kim, K, Yukawa, H, Shibata, H 1999Association of physical performance and falls among the community elderly in Japan in a 5-year follow-up study (in Japanese with English summary)Jpn J Geriatr36472478Google Scholar

Copyright information

© Springer-Verlag Tokyo 2006

Authors and Affiliations

  • Taiki Komatsu
    • 1
  • Kang Jung Kim
    • 3
  • Tetsuo Kaminai
    • 2
  • Hiroyasu Okuizumi
    • 4
  • Hiroharu Kamioka
    • 5
  • Shinpei Okada
    • 6
  • Hyuntae Park
    • 1
  • Ayumi Hasegawa
    • 1
  • Yoshiteru Mutoh
    • 1
  • Iwao Yamamoto
    • 7
  1. 1.Department of Physical and Health Education, Graduate School of EducationThe University of TokyoTokyoJapan
  2. 2.Department of RehabilitationTokyo Koseinenkin HospitalTokyoJapan
  3. 3.Department of Orthopedic SurgeryTokyo Women's Medical UniversityTokyoJapan
  4. 4.Department of Orthopedic SurgeryNational Center for Geriatrics and GerontologyObuJapan
  5. 5.Laboratory of Physical and Health Education, Faculty of Regional Environment ScienceTokyo University of AgricultureTokyoJapan
  6. 6.Laboratory of Physical Education and MedicineTomiJapan
  7. 7.Faculty of Textile Science and TechnologyShinshu UniversityUedaJapan

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