Reversible metastatic visceral calcification detected by 99mTc-methylene diphosphonate bone scanning in breast cancer
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Abstract
Diffuse metastatic visceral calcification is rare in breast cancer. We report on a 57-year-old woman with breast cancer and hypercalcemia who had diffuse metastatic visceral calcifications on lungs, myocardium, stomach, and thyroid on a 99mTc-methylene diphosphonate bone scan. Visceral calcifications were completely resolved 6 months after successful anticancer and zoledronic acid treatments. Bone scanning offers a useful diagnostic tool for both identifying visceral calcification and assessing the response to therapy in chemosensitive malignities with hypercalcemia such as breast cancer.
Key words
Breast cancer Visceral calcifications HypercalcemiaPreview
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References
- 1.Schmitz, N, Moreau, L, Pauli, G, Quoix, E 2001Metastatic gastric calcifications and bronchial neuroendocrine tumorRev Mal Respir18664666PubMedGoogle Scholar
- 2.Pavlovic, D 2003Pathologic calcification in patients with chronic kidney failureActa Med Croatica577782PubMedGoogle Scholar
- 3.Lorberboym, M, Bergman, D, Kim, CK 1995Metastatic calcification of multiple visceral organs in non-Hodgkin’s lymphomaJ Nucl Med36820821PubMedGoogle Scholar
- 4.Oursin, C, Meyer, E 1992An irritating cough in dialysis patients. A rare differential diagnosisRadiologe327779PubMedGoogle Scholar
- 5.Choy, D, Murray, IP 1980Metastatic visceral calcification identified by bone scanningSkeletal Radiol5151159PubMedGoogle Scholar
- 6.Watson, NW,Jr, Cowan, RJ, Maynard, CD, Richards, F 1977Resolution of metastatic calcification revealed by bone scanning: case reportJ Nucl Med18890892PubMedGoogle Scholar
- 7.Kempter, H, Hagner, G, Savaser, AN, Huben, H, Minguillon, C 1986Metastatic pulmonary calcification in a patient with nonsecretory multiple myelomaRespiration497780PubMedGoogle Scholar
- 8.Velentzas, C, Meindok, H, Oreopoulos, DG, Meema, HE, Rabinovich, S, Jones, M, Sutton, D, Rapoport, A, deVeber, GA 1978Visceral calcification and the Ca × P productAdv Exp Med Biol103195201PubMedGoogle Scholar
- 9.Amico, S, Lucas, P, Diebold, MD, Liehn, JC, Petit, J, Valeyre, J 1986Metastatic calcification in the thyroid gland demonstrated on bone scan in a patient with primary hyperparathyroidismJ Nucl Med27373376PubMedGoogle Scholar
- 10.Uchida, M, Yamato, H, Nagai, Y, Yamagiwa, H, Hayami, T, Tokunaga, K, Endo, N, Suzuki, H, Obara, K, Fujieda, A, Murayama, H, Fukumoto, S 2001Parathyroid hormone increases the expression level of matrix metalloproteinase-13 in vivoJ Bone Miner Metab19207212CrossRefPubMedGoogle Scholar
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© Springer-Verlag Tokyo 2005