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Gefässchirurgie

, Volume 23, Issue 8, pp 592–599 | Cite as

Ernährung und periphere arterielle Verschlusskrankheit – Teil 1

  • P. Daniels
  • E. S. Debus
  • R. T. Grundmann
Originalien
  • 35 Downloads

Zusammenfassung

Im Gegensatz zu den besser untersuchten Formen kardiovaskulärer Erkrankungen ist die Rolle der Ernährung bei der peripheren arteriellen Verschlusskrankheit (PAVK) wenig bekannt. Dies verdeutlicht die Tatsache, dass die aktuell verbreiteten PAVK-Leitlinien keine Ernährungsempfehlungen zur Prävention oder Behandlung der PAVK ausgeben. Grundsätzlich muss zwischen Ernährungsmustern und einzelnen Nährstoffen oder Nahrungsmitteln unterschieden werden. Zu den Nährstoffen gehört die Folsäure, ein Folsäuremangel konnte mit endothelialer Dysfunktion, Vasokonstriktion und Entzündungen in Verbindung gebracht werden. Eine ballaststoffreiche Ernährung ist mit einem verminderten Risiko für kardiovaskuläre Erkrankungen und kardiovaskuläre Ereignisse assoziiert. Allerdings haben bisher keine prospektiven Studien einen positiven Einfluss auf Entzündungsaktivität oder kardiovaskuläres Outcome bei PAVK-Patienten nachweisen können. Der Verzehr von Leinsamen, welche viel α‑Linolensäure enthalten, kann Patienten mit PAVK angeraten werden. Die klassische mediterrane Diät ist das traditionelle Ernährungsmuster, welches in den Gebieten des Olivenanbaus wie Kreta, Griechenland, Süditalien in den späten 50er und 60er Jahren des letzten Jahrhunderts zu finden war. Es ist eine relativ fettreiche Ernährung, hauptsächlich aus einfach ungesättigten Fettsäuren, mit Olivenöl als Hauptquelle von Fett. Hinzu kommt ein geringer Konsum an rotem Fleisch oder Fleischprodukten, und ein geringer bis moderater Konsum von Milch, Milchprodukten (meist Joghurt und Käse) und Wein. Eine Ernährung im mediterranen Stil ist sowohl in der primären als auch in der sekundären Prävention der PAVK effektiv.

Schlüsselwörter

Prävention Ernährung Folsäure Olivenöl Mediterrane Diät 

Nutrition and peripheral artery occlusive disease—Part 1

Abstract

In contrast to the better studied forms of cardiovascular diseases, the role of nutrition in peripheral arterial occlusive disease (PAOD) is poorly understood. This illustrates the fact that the current PAOD guidelines do not provide nutritional recommendations for the prevention or treatment of PAOD. Basically, a distinction must be made between nutritional patterns and individual nutrients or foods. The nutrients include folic acid and a folic acid deficiency could be associated with endothelial dysfunction, vasoconstriction and inflammation. A high-fiber diet is associated with a decreased risk of cardiovascular diseases and cardiovascular events; however, no prospective studies have been able to show a positive influence on inflammatory activity or cardiovascular outcome in PAOD patients. The consumption of linseed, which contains a lot of alpha-linolenic acid, may be recommended for patients with PAOD. The classical Mediterranean diet is the traditional food pattern found in olive growing areas, such as Crete, Greece and southern Italy in the late 1950s and 1960s. It is a relatively high-fat diet, mainly made from monounsaturated fatty acids, with olive oil as the main source of fat. In addition, there is a low consumption of red meat or meat products and a low to moderate consumption of milk, dairy products (mostly yoghurt and cheese) and wine. A Mediterranean-style diet is effective in both primary and secondary prevention of PAOD.

Keywords

Prevention Nutrition Folic acid Olive oil Mediterranean diet 

Notes

Einhaltung ethischer Richtlinien

Interessenkonflikt

P. Daniels, E.S. Debus und R.T. Grundmann geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

Literatur

  1. 1.
    Abdullah MM, Jones JP, Jones PJ (2015) Economic benefits of the mediterranean-style diet consumption in Canada and the United States. Food Nutr Res 59:27541CrossRefGoogle Scholar
  2. 2.
    Antonelli-Incalzi R, Pedone C, McDermott MM, Bandinelli S, Miniati B, Lova RM, Lauretani F, Ferrucci L (2006) Association between nutrient intake and peripheral artery disease: results from the InCHIANTI study. Atherosclerosis 186:200–206CrossRefGoogle Scholar
  3. 3.
    Bertoia ML, Pai JK, Cooke JP, Joosten MM, Mittleman MA, Rimm EB, Mukamal KJ (2014) Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease. Atherosclerosis 235:94–101CrossRefGoogle Scholar
  4. 4.
    Brostow DP, Hirsch AT, Collins TC, Kurzer MS (2012) The role of nutrition and body composition in peripheral arterial disease. Nat Rev Cardiol 9:634–643CrossRefGoogle Scholar
  5. 5.
    Brostow DP, Hirsch AT, Pereira MA, Bliss RL, Kurzer MS (2016) Nutritional status and body composition in patients with peripheral arterial disease: a cross-sectional examination of disease severity and quality of life. Ecol Food Nutr 55:87–109CrossRefGoogle Scholar
  6. 6.
    Bunout D, Petermann M, Hirsch S, De La Maza P, Suazo M, Barrera G, Kauffman R (2000) Low serum folate but normal homocysteine levels in patients with atherosclerotic vascular disease and matched healthy controls. Nutrition 16:434–438CrossRefGoogle Scholar
  7. 7.
    Caligiuri SP, Rodriguez-Leyva D, Aukema HM, Ravandi A, Weighell W, Guzman R, Pierce GN (2016) Dietary flaxseed reduces central aortic blood pressure without cardiac involvement but through changes in plasma oxylipins. Hypertension 68:1031–1038CrossRefGoogle Scholar
  8. 8.
    Ciccarone E, Di Castelnuovo A, Salcuni M, Siani A, Giacco A, Donati MB, De Gaetano G, Capani F, Iacoviello L (2003) A high-score mediterranean dietary pattern is associated with a reduced risk of peripheral arterial disease in Italian patients with type 2 diabetes. J Thromb Haemost 1:1744–1752CrossRefGoogle Scholar
  9. 9.
    Donnan PT, Thomson M, Fowkes FG, Prescott RJ, Housley E (1993) Diet as a risk factor for peripheral arterial disease in the general population: the Edinburgh Artery Study. Am J Clin Nutr 57:917–921CrossRefGoogle Scholar
  10. 10.
    Eckel RH, Jakicic JM, Ard JD, De Jesus JM, Houston Miller N, Hubbard VS, Lee IM, Lichtenstein AH, Loria CM, Millen BE, Nonas CA, Sacks FM, Smith SC Jr., Svetkey LP, Wadden TA, Yanovski SZ, Kendall KA, Morgan LC, Trisolini MG, Velasco G, Wnek J, Anderson JL, Halperin JL, Albert NM, Bozkurt B, Brindis RG, Curtis LH, Demets D, Hochman JS, Kovacs RJ, Ohman EM, Pressler SJ, Sellke FW, Shen WK, Smith SC Jr., Tomaselli GF (2014) 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129:S76–S99CrossRefGoogle Scholar
  11. 11.
    Fowkes FG, Aboyans V, Fowkes FJ, McDermott MM, Sampson UK, Criqui MH (2017) Peripheral artery disease: epidemiology and global perspectives. Nat Rev Cardiol 14:156–170CrossRefGoogle Scholar
  12. 12.
    Gerhard-Herman MD, Gornik HL, Barrett C, Barshes NR, Corriere MA, Drachman DE, Fleisher LA, Fowkes FG, Hamburg NM, Kinlay S, Lookstein R, Misra S, Mureebe L, Olin JW, Patel RA, Regensteiner JG, Schanzer A, Shishehbor MH, Stewart KJ, Treat-Jacobson D, Walsh ME (2017) 2016 AHA/ACC guideline on the management of patients with lower extremity peripheral artery disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation 135:e686–e725Google Scholar
  13. 13.
    Aboyans V, Ricco J‑B, Bartelink M‑LEL, Björck M, Brodmann M, Cohnert T, Collet J‑P, Czerny M, de Carlo M, Debus S, Espinola-Klein C, Kahan T, Kownator S, Mazzolai L, Naylor AR, Roffi M, Röther J, Sprynger M, Tendera M, Tepe G, Venermo M, Vlachopoulos C, Desormais I, Group, E. S. C. S. D. (2018) 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European Society For Vascular Surgery (ESVS) document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteriesendorsed by: the European Stroke Organization (ESO) the task force for the diagnosis and treatment of peripheral arterial diseases of the European Society of Cardiology (ESC) and of the European society For Vascular Surgery (ESVS). Eur Heart J 39:763–816CrossRefGoogle Scholar
  14. 14.
    Heffron SP, Rockman CB, Adelman MA, Gianos E, Guo Y, Xu J, Berger JS (2017) Greater frequency of fruit and vegetable consumption is associated with lower prevalence of peripheral artery disease. Arterioscler Thromb Vasc Biol 37:1234–1240CrossRefGoogle Scholar
  15. 15.
    Hoevenaar-Blom MP, Nooyens AC, Kromhout D, Spijkerman AM, Beulens JW, Van Der Schouw YT, Bueno-De-Mesquita B, Verschuren WM (2012) Mediterranean style diet and 12-year incidence of cardiovascular diseases: the EPIC-NL cohort study. PLoS ONE 7:e45458CrossRefGoogle Scholar
  16. 16.
    Hung HC, Merchant A, Willett W, Ascherio A, Rosner BA, Rimm E, Joshipura KJ (2003) The association between fruit and vegetable consumption and peripheral arterial disease. Epidemiology 14:659–665CrossRefGoogle Scholar
  17. 17.
    Katsouyanni K, Skalkidis Y, Petridou E, Polychronopoulou-Trichopoulou A, Willett W, Trichopoulos D (1991) Diet and peripheral arterial occlusive disease: the role of poly-, mono-, and saturated fatty acids. Am J Epidemiol 133:24–31CrossRefGoogle Scholar
  18. 18.
    Kim DH, Sabour S, Sagar UN, Adams S, Whellan DJ (2008) Prevalence of hypovitaminosis D in cardiovascular diseases (from the National Health and Nutrition Examination Survey 2001 to 2004). Am J Cardiol 102:1540–1544CrossRefGoogle Scholar
  19. 19.
    Klipstein-Grobusch K, Den Breeijen JH, Grobbee DE, Boeing H, Hofman A, Witteman JCM (2001) Dietary antioxidants and peripheral arterial disease the Rotterdam Study. Epidemiol Rev 154:145–149Google Scholar
  20. 20.
    Kuan Y‑M, Dear AE, Grigg MJ (2002) Homocysteine: an aetiological contributor to peripheral vascular arterial disease. ANZ J Surg 72:668–671CrossRefGoogle Scholar
  21. 21.
    Lagiou P, Samoli E, Lagiou A, Skalkidis Y, Katsouyanni K, Petridou E, Trichopoulos D (2006) Flavonoid classes and risk of peripheral arterial occlusive disease: a case-control study in Greece. Eur J Clin Nutr 60:214–219CrossRefGoogle Scholar
  22. 22.
    Lane JS, Magno CP, Lane KT, Chan T, Hoyt DB, Greenfield S (2008) Nutrition impacts the prevalence of peripheral arterial disease in the United States. J Vasc Surg 48:897–904CrossRefGoogle Scholar
  23. 23.
    Lawall H, Huppert P, Rümenapf G (2015) S3-Leitlinie zur Diagnostik, Therapie und Nachsorge der peripheren arteriellen Verschlusskrankheit. AWMF-Register Nr. 065/003 Entwicklungsstufe 3 (Deutsche Gesellschaft für Angiologie – Gesellschaft für Gefäßmedizin: http://www.awmf.org/leitlinien/detail/ll/065-003.html)Google Scholar
  24. 24.
    Leng GC, Horrobin DF, Fowkes FG, Smith FB, Lowe GD, Donnan PT, Ells K (1994) Plasma essential fatty acids, cigarette smoking, and dietary antioxidants in peripheral arterial disease. A population-based case-control study. Arterioscler Thromb 14:471–478CrossRefGoogle Scholar
  25. 25.
    Mattei J, Sotres-Alvarez D, Gellman M, Castaneda SF, Hu FB, Tucker KL, Siega-Riz AM, Kaplan RC (2018) Diet quality, inflammation, and the ankle brachial index in adults with or without cardiometabolic conditions. Clin Nutr 37(4):1332–1339.  https://doi.org/10.1016/j.clnu.2017.06.003 CrossRefGoogle Scholar
  26. 26.
    Mattioli AV, Palmiero P, Manfrini O, Puddu PE, Nodari S, Dei Cas A, Mercuro G, Scrutinio D, Palermo P, Sciomer S, di Francesco S, Novo G, Novo S, Pedretti RFE, Zito A, Parati G, Pedrinelli R, Farinetti A, Maiello M, Moscucci F, Tenaglia RL, Sucato V, Triggiani M, Cugusi L, Scicchitano P, Saba PS, Ciccone MM (2017) Mediterranean diet impact on cardiovascular diseases: a narrative review. J Cardiovasc Med (Hagerstown) 18:925–935CrossRefGoogle Scholar
  27. 27.
    Mazidi M, Wong ND, Katsiki N, Mikhailidis DP, Banach M (2017) Dietary patterns, plasma vitamins and trans fatty acids are associated with peripheral artery disease. Lipids Health Dis 16:254CrossRefGoogle Scholar
  28. 28.
    Melamed ML, Muntner P, Michos ED, Uribarri J, Weber C, Sharma J, Raggi P (2008) Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004. Arterioscler Thromb Vasc Biol 28:1179–1185CrossRefGoogle Scholar
  29. 29.
    Merchant AT, Hu FB, Spiegelman D, Willett WC, Rimm EB, Ascherio A (2003a) Dietary fiber reduces peripheral arterial disease risk in men. J Nutr 133:3658–3663CrossRefGoogle Scholar
  30. 30.
    Merchant AT, Hu FB, Spiegelman D, Willett WC, Rimm EB, Ascherio A (2003b) The use of B vitamin supplements and peripheral arterial disease risk in men are inversely related. J Nutr 133:2863–2867CrossRefGoogle Scholar
  31. 31.
    Mokdad AH, Ballestros K, Echko M, Glenn S, Olsen HE, Mullany E, Lee A, Khan AR, Ahmadi A, Ferrari AJ, Kasaeian A, Werdecker A, Carter A, Zipkin B, Sartorius B, Serdar B, Sykes BL, Troeger C, Fitzmaurice C, Rehm CD, Santomauro D, Kim D, Colombara D, Schwebel DC, Tsoi D, Kolte D, Nsoesie E, Nichols E, Oren E, Charlson FJ, Patton GC, Roth GA, Hosgood HD, Whiteford HA, Kyu H, Erskine HE, Huang H, Martopullo I, Singh JA, Nachega JB, Sanabria JR, Abbas K, Ong K, Tabb K, Krohn KJ, Cornaby L, Degenhardt L, Moses M, Farvid M, Griswold M, Criqui M, Bell M, Nguyen M, Wallin M, Mirarefin M, Qorbani M, Younis M, Fullman N, Liu P, Briant P, Gona P, Havmoller R, Leung R, Kimokoti R, Bazargan-Hejazi S, Hay SI, Yadgir S, Biryukov S, Vollset SE, Alam T, Frank T, Farid T, Miller T, Vos T, Barnighausen T, Gebrehiwot TT, Yano Y, Al-Aly Z, Mehari A, Handal A, Kandel A, Anderson B, Biroscak B, Mozaffarian D, Dorsey ER, Ding EL, Park EK, Wagner G, Hu G, Chen H, Sunshine JE, Khubchandani J, Leasher J, Leung J, Salomon J, Unutzer J, Cahill L, Cooper L, Horino M, Brauer M et al (2018) The state of US health, 1990–2016: burden of diseases, injuries, and risk factors among US states. JAMA 319:1444–1472CrossRefGoogle Scholar
  32. 32.
    Moore LV, Dodd KW, Thompson FE, Grimm KA, Kim SA, Scanlon KS (2015) Using behavioral risk factor surveillance system data to estimate the percentage of the population meeting US Department of Agriculture food patterns fruit and vegetable intake recommendations. Am J Epidemiol 181:979–988CrossRefGoogle Scholar
  33. 33.
    Naqvi AZ, Davis RB, Mukamal KJ (2012) Dietary fatty acids and peripheral artery disease in adults. Atherosclerosis 222:545–550CrossRefGoogle Scholar
  34. 34.
    Naqvi AZ, Davis RB, Mukamal KJ (2014) Nutrient intake and peripheral artery disease in adults: key considerations in cross-sectional studies. Clin Nutr 33:443–447CrossRefGoogle Scholar
  35. 35.
    Nosova EV, Bartel K, Chong KC, Alley HF, Conte MS, Owens CD, Grenon SM (2015) Analysis of nutritional habits and intake of polyunsaturated fatty acids in veterans with peripheral arterial disease. Vasc Med 20:432–438CrossRefGoogle Scholar
  36. 36.
    Rodriguez-Leyva D, Weighell W, Edel AL, Lavallee R, Dibrov E, Pinneker R, Maddaford TG, Ramjiawan B, Aliani M, Guzman R, Pierce GN (2013) Potent antihypertensive action of dietary flaxseed in hypertensive patients. Hypertension 62:1081–1089CrossRefGoogle Scholar
  37. 37.
    Ruiz-Canela M, Martinez-Gonzalez MA (2014) Lifestyle and dietary risk factors for peripheral artery disease. Circ J 78:553–559CrossRefGoogle Scholar
  38. 38.
    Ruiz-Canela M, Estruch R, Corella D, Salas-Salvado J, Martinez-Gonzalez MA (2014) Association of mediterranean diet with peripheral artery disease: the PREDIMED randomized trial. JAMA 311:415–417CrossRefGoogle Scholar
  39. 39.
    Strazzullo P, D’Elia L, Kandala NB, Cappuccio FP (2009) Salt intake, stroke, and cardiovascular disease: meta-analysis of prospective studies. BMJ 339:b4567CrossRefGoogle Scholar
  40. 40.
    Sugiura T, Yoshikawa D, Ishii H, Suzuki S, Kumagai S, Inoue Y, Okumura S, Isobe S, Hayashi M, Ando H, Amano T, Murohara T (2014) Relation of omega-3 fatty acid and C‑reactive protein to peripheral artery disease in patients with coronary artery disease. Heart Vessels 29:449–455CrossRefGoogle Scholar
  41. 41.
    Gimeno SGA, Hirai A, Harima HA, Kikuchi M, Simony RF, Barros ND Jr., Cardoso MA, Ferreira SRG, The Japanese-Brazilian Diabetes Study Group (2008) Fat and fiber consumption are associated with peripheral arterial disease in a cross-sectional study of a Japanese-Brazilian population. Circ J 72:44–50CrossRefGoogle Scholar
  42. 42.
    Törnwall ME, Virtamo J, Haukka JK, Aro A, Albanes D, Huttunen JK (2000) Prospective study of diet, lifestyle, and intermittent claudication in male smokers. Epidemiol Rev 151:892–901Google Scholar
  43. 43.
    Vaidya A, Bentley-Lewis R, Jeunemaitre X, Adler GK, Williams JS (2009) Dietary sodium alters the prevalence of electrocardiogram determined left ventricular hypertrophy in hypertension. Am J Hypertens 22:669–673CrossRefGoogle Scholar
  44. 44.
    Wilmink AB, Welch AA, Quick CR, Burns PJ, Hubbard CS, Bradbury AW, Day NE (2004) Dietary folate and vitamin B6 are independent predictors of peripheral arterial occlusive disease. J Vasc Surg 39:513–516CrossRefGoogle Scholar

Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Klinik und Poliklinik für GefäßmedizinUniversitäres Herzzentrum Hamburg, Universitätsklinikum Hamburg-EppendorfHamburgDeutschland
  2. 2.BurghausenDeutschland

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